GNAI2 anticorps
Aperçu rapide pour GNAI2 anticorps (ABIN127055)
Antigène
Voir toutes GNAI2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- The antibody detects human Gαi2. It also cross-reacts with Gαi3 and partially with Gαi1.
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Purification
- Affinity chromatography
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anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) (AA 1-355) antibody
GNAI2 Reactivité: Humain WB, ELISA, PLA Hôte: Souris Monoclonal 3G11 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) (AA 1-355) antibodyGNAI2 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) antibodyGNAI2 Reactivité: Humain, Souris, Rat IF Hôte: Lapin Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) (AA 1-339) antibodyGNAI2 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 2E4 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) (AA 289-299) antibodyVerified GNAI2 Reactivité: Humain WB, IHC, ELISA Hôte: Chèvre Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) antibodyGNAI2 Reactivité: Humain WB, IHC Hôte: Lapin Monoclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) antibodyGNAI2 Reactivité: Humain, Souris, Rat WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) (Center) antibodyGNAI2 Reactivité: Humain WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) antibodyGNAI2 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB410 unconjugated Recombinant Antibody
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2) antibodyGNAI2 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Western blot (0.5-1 μg/mL). Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid Repeated freeze/defrost cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. For long term storage, aliquot and freeze at -70 °C.
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- GNAI2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2))
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Sujet
- Gαi2 is a 40-41 kDa alpha-subunit of heterotrimeric protein, that shares sequence homology with Gαi3 and Gαi1. All these G proteins can be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Gαi2 is expressed widely in tissues and cell lines. Activation of PLC-β by Gαi-coupled receptors is the result of release of Gβγ subunits from Gαi. Gαi2 regulates potassium channel activation. Mutation at Arg179 has been identified in tumors. This and the Q205L mutant inhibit adenylyl cyclase.Synonyms: Adenylate cyclase-inhibiting G alpha protein, GNAI2, GNAI2B, Guanine nucleotide-binding protein G(i), alpha-2 subunit
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ID gène
- 2771
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NCBI Accession
- NP_002061
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UniProt
- P04899
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Pathways
- cAMP Metabolic Process, G-protein mediated Events, Thromboxane A2 Receptor Signaling
Antigène
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