G Protein-Coupled Receptor 119 anticorps
Aperçu rapide pour G Protein-Coupled Receptor 119 anticorps (ABIN317642)
Antigène
Voir toutes G Protein-Coupled Receptor 119 (GPR119) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of GPR119 protein.(region surrounding Val227)
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Purification
- Affinity Chromatography using epitope-specific immunogen.
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anti-G Protein-Coupled Receptor 119 (GPR119) (Cytoplasmic Domain) antibody
GPR119 Reactivité: Humain, Roussette (Chauve-souris) IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) antibodyGPR119 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Cytoplasmic Domain) antibodyGPR119 Reactivité: Humain IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Internal Region) antibodyGPR119 Reactivité: Humain, Souris WB, ELISA, IF, IHC, ICC Hôte: Lapin Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Internal Region) antibodyGPR119 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Center) antibodyGPR119 Reactivité: Humain, Singe WB, IF, IHC Hôte: Lapin Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) antibodyGPR119 Reactivité: Humain, Souris, Rat, Chien ELISA, IF, BP Hôte: Lapin Chimeric Gipg013 unconjugated Recombinant Antibody
anti-G Protein-Coupled Receptor 119 (GPR119) (C-Term) antibodyVerified GPR119 Reactivité: Humain WB, ELISA Hôte: Chèvre Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (AA 186-235) antibodyGPR119 Reactivité: Humain WB, ELISA, IF, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (3rd Cytoplasmic Domain) antibodyGPR119 Reactivité: Humain IHC (p) Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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ELISA: 1/1000-1/5000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- G Protein-Coupled Receptor 119 (GPR119)
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Autre désignation
- GPR119
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Sujet
- G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intra cellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane- spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR119 is a 335 amino acid protein that is mainly expressed in the pancreas. It is an endogenous receptor for lysophosphatidylcholine (LPC), which is is a lipid mediator involved in insulin secretion from pancreatic cells. GPR119 may participate in this insulin secretion, suggesting that it may be potential target for new anti-diabetic drugs.Synonyms: G-protein coupled receptor 119, Glucose-dependent insulinotropic receptor
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Poids moléculaire
- approx. 37 kDa
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ID gène
- 139760
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NCBI Accession
- NP_848566
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UniProt
- Q8TDV5
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Pathways
- Hormone Transport, Peptide Hormone Metabolism
Antigène
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