GRM7 anticorps (Extracellular Domain, N-Term)
Aperçu rapide pour GRM7 anticorps (Extracellular Domain, N-Term) (ABIN122636)
Antigène
Voir toutes GRM7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Extracellular Domain, N-Term
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Specificité
- This antibody detects mGluR7 / GRM7 at N-term. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GRM4 (60 %), GRM6 (45 %).
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Réactivité croisée (Details)
- Species reactivity (expected):Mouse, Rat (Others see 'Immunogen Remarks')Species reactivity (tested):Human
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Purification
- Immunoaffinity chromatography
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Immunogène
- Synthetic peptide - KLH conjugated
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anti-Glutamate Receptor, Metabotropic 7 (GRM7) (AA 454-590) antibody
GRM7 Reactivité: Humain ELISA, FACS, ICC Hôte: Souris Monoclonal 7G8D3 unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (AA 454-590) antibodyGRM7 Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 7G8A2 unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) antibodyGRM7 Reactivité: Humain, Rat, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (N-Term) antibodyGRM7 Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cheval, Singe WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (N-Term) antibodyGRM7 Reactivité: Humain, Rat, Souris, Chien, Lapin, Boeuf (Vache), Cheval, Singe, Poulet IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (Extracellular Domain) antibodyGRM7 Reactivité: Humain, Rat, Souris, Chien, Lapin, Boeuf (Vache), Cheval, Singe, Porc IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (AA 377-390), (Extracellular) antibodyGRM7 Reactivité: Rat WB, IHC, IF, FACS, IC, LCI Hôte: Lapin Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) antibodyGRM7 Reactivité: Humain, Rat, Souris WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) antibodyGRM7 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 7 (GRM7) (N-Term) antibodyGRM7 Reactivité: Humain, Boeuf (Vache) WB, IHC, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Western Blot. Immunohistochemistry with formalin fixed paraffin embedded tissues: 7 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.09 % Sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-80 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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Autre désignation
- mGluR7 / GRM7
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Sujet
- Metabotropic glutamate receptor GRM7 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. GRM7 is highly concentrated at presynaptic terminals and is thought to play an important role in the modulation of glutamatergic synaptic transmission by effecting presynaptic inhibition of glutamate release. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group III includes GRM4, GRM6, GRM7, and GRM8 receptors, which are linked to inhibition of the cyclic AMP signaling cascade. Five mRNA variants of GRM7 have been described, most of the variants are expressed in brain and retina, although there are non-neuronal variants that may have different functional properties. GRM7 has been reported to be expressed in active zones of presynaptic axon terminals in various regions of the brain, eye, and spinal cord.Synonyms: GPRC1G, MGLUR7, Metabotropic glutamate receptor 7
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ID gène
- 2917
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UniProt
- Q14831
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Pathways
- Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
Antigène
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