HAT1 anticorps
Aperçu rapide pour HAT1 anticorps (ABIN498132)
Antigène
Voir toutes HAT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of HAT1 protein.
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography using epitope-specific immunogen
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Pureté
- > 95 % (by SDS-PAGE)
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anti-Histone Acetyltransferase 1 (HAT1) antibody
HAT1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Monoclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 245-419), (Catalytic Subunit) antibodyHAT1 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) antibodyKD Validated HAT1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB2090 unconjugated Recombinant Antibody
anti-Histone Acetyltransferase 1 (HAT1) (AA 245-419), (Catalytic Subunit) antibodyHAT1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 389-419), (C-Term) antibodyHAT1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB5769 unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (C-Term) antibodyHAT1 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 100-338) antibodyHAT1 Reactivité: Souris WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 331-380) antibodyHAT1 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 369-419) antibodyHAT1 Reactivité: Humain, Souris WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 27-58), (N-Term) antibodyHAT1 Reactivité: Humain WB Hôte: Lapin Polyclonal RB5768 unconjugated
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Indications d'application
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- HAT1 (Histone Acetyltransferase 1 (HAT1))
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Autre désignation
- HAT1
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Sujet
- In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBPassociated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.Synonyms: Histone acetyltransferase type B catalytic subunit
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Poids moléculaire
- approx. 49 kDa
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ID gène
- 8520
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NCBI Accession
- NP_003633
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UniProt
- O14929
Antigène
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