HBP1 anticorps
Aperçu rapide pour HBP1 anticorps (ABIN272139)
Antigène
Voir toutes HBP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of HBP1 protein. (region surrounding Leu468)
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Pureté
- > 95 % pure by SDS-PAGE
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anti-HMG Box-Containing Protein 1 (HBP1) (C-Term) antibody
HBP1 Reactivité: Humain, Souris, Rat, Singe WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (AA 421-514) antibodyHBP1 Reactivité: Souris WB, ELISA, IHC (p), ICC, IF (cc), IF (p) Hôte: Lapin Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (AA 1-514) antibodyHBP1 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (C-Term) antibodyHBP1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (C-Term) antibodyHBP1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Singe, Cobaye, Poulet, Cheval, Lapin, Xenopus laevis, Roussette (Chauve-souris), Porc WB Hôte: Lapin Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (AA 396-445) antibodyHBP1 Reactivité: Humain, Rat, Chien, Singe, Cobaye WB Hôte: Lapin Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (Middle Region) antibodyHBP1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien WB Hôte: Lapin Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (Middle Region) antibodyHBP1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet, Poisson zèbre (Danio rerio), Xenopus laevis WB Hôte: Lapin Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (N-Term) antibodyHBP1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet, Xenopus laevis WB Hôte: Lapin Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (pSer402) antibodyHBP1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- DO NOT FREEZE!
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- HBP1 (HMG Box-Containing Protein 1 (HBP1))
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Autre désignation
- HBP1
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Sujet
- The HMG-box protein-1 (HBP1) is a member of the HMG family of transcription factors, which are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, that mediates DNA binding. HBP1 binds to the tumor suppressor proteins Rb and p130 and initiates cell cycle arrest. Terminal cell differentiation requires this initial cell cycle arrest followed by the coordinated expression of genes defined as tissue-specifc markers. Along with initiating the commitment to cell differentiation, the continued activity of HBP1 abrogates the expression of tissue-specific genes by associating with the MyoD proteins. In muscle cell differentiation, the MyoD family of transcription factors, which include Myf5, MyoD and myogenein, induce the expression of these cell-type specific proteins and contribute to the development of cell phenotypes. The progression of terminal differentiation is, therefore, dependent on both a decrease in HBP1 activity and the corresponding activation of MyoD-induced gene transcription.Synonyms: HMG box transcription factor 1, HMG box-containing protein 1, High mobility group box transcription factor 1
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Poids moléculaire
- approx. 50 kDa
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ID gène
- 26959
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NCBI Accession
- NP_036389
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UniProt
- O60381
Antigène
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