Laminin gamma 1 anticorps
Aperçu rapide pour Laminin gamma 1 anticorps (ABIN498386)
Antigène
Voir toutes Laminin gamma 1 (LAMC1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- This antibody detects endogenous levels of Laminin gamma-1 protein. (region surrounding Glu1472)
-
Réactivité croisée (Details)
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- Affinity Chromatography using epitope-specific immunogen.
-
-
anti-Laminin, gamma 1 (LAMC1) (all Isoforms) antibody
LAMC1 Reactivité: Humain, Souris, Rat WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1300-1609) antibodyLAMC1 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 Reactivité: Humain WB, ELISA, PLA Hôte: Souris Monoclonal M1 unconjugated
anti-Laminin, gamma 1 (LAMC1) antibodyKD Validated LAMC1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 24GB5925 unconjugated Recombinant Antibody
anti-Laminin, gamma 1 (LAMC1) (AA 521-772) antibodyLAMC1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 2E6-B4 unconjugated
anti-Laminin, gamma 1 (LAMC1) (N-Term) antibodyLAMC1 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) antibodyLAMC1 Reactivité: Souris Hôte: Lapin Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1333-1607) antibodyLAMC1 Reactivité: Humain IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1566-1579) antibodyLAMC1 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
-
-
Indications d'application
-
Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.09 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
-
Autre désignation
- Laminin gamma 1
-
Sujet
- Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of Laminins with stabilizing Type IV Collagen networks, Nidogen and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression and tissue architecture. Each Laminin is a heterotrimer of alpha, beta and gamma chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules and have unique and shared cell interactions mediated by Integrins, dystroglycan and cognate Laminin receptors. The human Laminin gamma-1 gene maps to chromosome 1q31 and is ubiquitously expressed in tissues that produce basement membranes.Synonyms: LAMB2, LAMC1, Laminin B2 chain, Laminin subunit gamma-1
-
Poids moléculaire
- approx. 178.0 kDa
-
ID gène
- 3915
-
NCBI Accession
- NP_002284
-
UniProt
- P11047
Antigène
-
