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PPP1R13L anticorps (AA 775-800)

Cet anticorps Lapin Polyclonal détecte spécifiquement PPP1R13L dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.
Rockland
N° du produit ABIN129682
N° du produit (Fournisseur): 600-401-926
624,85 €
Frais d'envoi 40,00 €, glace carbonique 20,00 € et TVA exclus
Destination: France
Envoi sous 5 à 8 jours ouvrables

Aperçu rapide pour PPP1R13L anticorps (AA 775-800) (ABIN129682)

Antigène

Voir toutes PPP1R13L Anticorps
PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))

Reactivité

  • 57
  • 23
  • 21
  • 7
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
Humain

Hôte

  • 52
  • 5
Lapin

Clonalité

  • 55
  • 2
Polyclonal

Conjugué

  • 32
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PPP1R13L est non-conjugé

Application

  • 45
  • 17
  • 16
  • 14
  • 13
  • 10
  • 10
  • 9
  • 3
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Épitope

    • 16
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 775-800

    N° du produit (Fournisseur)

    600-401-926

    Fournisseur

    Rockland

    Fonction

    iASSP Antibody

    Réactivité croisée (Details)

    This affinity-purified antibody is directed against the human iASPP protein.

    Attributs du produit

    Synonyms: rabbit anti-iASPP antibody, inhibitor of apoptosis stimulating protein of p53 antibody, Inhibitor of ASPP protein antibody, RelA-associated inhibitor, NFkB interacting protein 1 antibody, Protein iASPP, NKIP1 antibody, PPP1R13B-like protein antibody, IASPP, NKIP1, PPP1R13BL, RAI, PPP1R13L

    Purification

    The product was affinity purified from monospecific antiserum by immunoaffinity purification.

    Stérilité

    Sterile filtered

    Immunogène

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 775-800 of human iASPP (isoform 1) protein.

    Immunogen Type: Conjugated Peptide

    Isotype

    IgG
  • Indications d'application

    Immunohistochemistry Dilution: 1:1,000 - 1:5,000

    Application Note: This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and by western blot.  Specific conditions for reactivity should be optimized by the end user.  Expect bands approximately 100 kDa and 50 kDa in size corresponding to isoforms 1 and 2 respectively of iASPP protein by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:1,000 - 1:5,000

    ELISA Dilution: 1:40,000 - 1:160,000

    Other: User Optimized

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.0 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Date de péremption

    12 months
  • Liu, Lu, Zhong: "ASPP--Apoptotic specific regulator of p53." dans: Biochimica et biophysica acta, Vol. 1756, Issue 1, pp. 77-80, (2005) (PubMed).

  • Antigène

    PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))

    Autre désignation

    PPP1R13L

    Sujet

    Background: ASPP proteins (ASPP1, ASPP2 and iASPP) represent a new family of p53 binding proteins.  ASPP1 and ASPP2 bind and enhance p53-mediated apoptosis. In contrast, the third member, iASPP, functionally inactivates p53.  iASPP (also called protein phosphatase 1 regulatory (inhibitor) subunit 13 like protein, Inhibitor of ASPP protein, Protein iASPP, PPP1R13B-like protein and NFkB-interacting protein 1) plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. iASPP blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1.

    ID gène

    10848, 63003907

    UniProt

    Q8WUF5
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