Il existe 2+ publications pour ce produit.
L’anticorps anti-SLC29A1 Polyclonal Lapin est utilisé pour la détection de SLC29A1 dans des échantillons de Humain et Souris. Il a été validé pour WB.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This ENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-263 amino acids from the Central region of rat ENT1(O54698).
Ibarra, Pfeiffer: "Reduced ribavirin antiviral efficacy via nucleoside transporter-mediated drug resistance." dans: Journal of virology, Vol. 83, Issue 9, pp. 4538-47, (2009) (PubMed).
Antigène
SLC29A1
(Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))
Autre désignation
ENT1
Sujet
ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.