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TRPM7 anticorps (C-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement TRPM7 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain et Souris. Il a été cité dans 2+ publications.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (TRPM7 anticorps (C-Term))

IHC (p)

CHAK1 Antibody (ABIN392614 and ABIN2837991) western blot analysis in 293 cell line lysates (35 μg/lane). (TRPM7 anticorps (C-Term))

3 images

(2 références)

N° du produit ABIN392614

434,77 €

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Destination: France

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Aperçu rapide pour TRPM7 anticorps (C-Term) (ABIN392614)

Antigène

Voir toutes TRPM7 Anticorps

TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Reactivité

Humain, Souris

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp TRPM7 est non-conjugé

Application

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB3469-3470

Discover our top product TRPM7 Anticorps primaire

Épitope
15

11

8

7

7

3

2

2

2

2

1

1

1

1

1

1
AA 1821-1850, C-Term

Homologie

Rat

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène

This TRPM7 (CHAK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1821-1850 amino acids from the C-terminal region of human TRPM7 (CHAK1).

Isotype

Ig Fraction
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 19-179) antibody
TRPM7 Reactivité: Rat WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody
TRPM7 Reactivité: Souris WB, IHC, ICC, IF, AA Hôte: Souris Monoclonal S74 unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (Biotin)
TRPM7 Reactivité: Souris WB, IHC, ICC, IF, AA Hôte: Souris Monoclonal S74 Biotin

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (FITC)
TRPM7 Reactivité: Souris WB, IHC, ICC, IF, AA Hôte: Souris Monoclonal S74 FITC

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (APC)
TRPM7 Reactivité: Souris WB, IHC, ICC, IF, AA Hôte: Souris Monoclonal S74 APC

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (HRP)
TRPM7 Reactivité: Souris WB, IHC, ICC, IF, AA Hôte: Souris Monoclonal S74 HRP

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (Atto 594)
TRPM7 Reactivité: Souris WB, IHC, ICC, IF, AA Hôte: Souris Monoclonal S74 Atto 594

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (PerCP)
TRPM7 Reactivité: Souris WB, IHC, ICC, IF, AA Hôte: Souris Monoclonal S74 PerCP

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (PE)
TRPM7 Reactivité: Souris WB, IHC, ICC, IF, AA Hôte: Souris Monoclonal S74 PE

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (Atto 488)
TRPM7 Reactivité: Souris WB, IHC, ICC, IF, AA Hôte: Souris Monoclonal S74 Atto 488

Indications d'application

WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Inoue, Branigan, Xiong: "Zinc-induced neurotoxicity mediated by transient receptor potential melastatin 7 channels." dans: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7430-9, (2010) (PubMed).

Gavenis, Schumacher, Schneider, Eisfeld, Mollenhauer, Schmidt-Rohlfing: "Expression of ion channels of the TRP family in articular chondrocytes from osteoarthritic patients: changes between native and in vitro propagated chondrocytes." dans: Molecular and cellular biochemistry, Vol. 321, Issue 1-2, pp. 135-43, (2009) (PubMed).
Antigène

TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Autre désignation

TRPM7 (CHAK1)

Sujet

TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM]

Poids moléculaire

212697

ID gène

54822

NCBI Accession

NP_060142

UniProt

Q96QT4