UACA anticorps (AA 311-410) (HRP)
Aperçu rapide pour UACA anticorps (AA 311-410) (HRP) (ABIN717200)
Antigène
Voir toutes UACA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 311-410
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Homologie
- Human,Mouse,Rat,Cow,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human UACA
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))
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Autre désignation
- UACA
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Sujet
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Synonyms: NUCLING, Uveal autoantigen with coiled-coil domains and ankyrin repeats, UACA, KIAA1561
Background: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury (By similarity).
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ID gène
- 55075
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UniProt
- Q9BZF9
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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