UBA7 anticorps
Aperçu rapide pour UBA7 anticorps (ABIN271972)
Antigène
Voir toutes UBA7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of UBE1L protein. (region surrounding Glu996)
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Pureté
- > 95 % pure by SDS-PAGE
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Indications d'application
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- DO NOT FREEZE!
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))
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Autre désignation
- UBA7 / UBE1L
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Sujet
- The ubiquitin activating enzyme E1 (UBE1) catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. UBE1 activates ubiquitin by first adenylating with ATP its carboxy-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. UBE1 is an example of an X-Y homologous gene, which is X-linked with a distinct Y-linked gene in many mammals. However, no UBE1 homolog is detectable on the human Y chromosome. UBE1 is thought to escape X inactivation in humans.Synonyms: UBE2, Ubiquitin-activating enzyme 7, Ubiquitin-activating enzyme E1 homolog, Ubiquitin-like modifier-activating enzyme 7
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Poids moléculaire
- approx. 112 kDa
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ID gène
- 7318
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NCBI Accession
- NP_003326
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UniProt
- P41226
Antigène
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