VDAC1 anticorps (N-Term)
(1 reference)Aperçu rapide pour VDAC1 anticorps (N-Term) (ABIN390563)
Antigène
Voir toutes VDAC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-30, N-Term
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Homologie
- B, Pig, Rb, Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This VDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human VDAC1.
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Isotype
- Ig Fraction
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anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 154-181), (Middle Region) antibody
VDAC1 Reactivité: Humain, Rat, Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Atto 488)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 Atto 488
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Atto 390)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 Atto 390
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Biotin)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 Biotin
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (APC)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 APC
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (PerCP)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 PerCP
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (PE)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 PE
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Atto 594)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 Atto 594
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (FITC)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 FITC
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (HRP)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 HRP
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Indications d'application
- WB: 1:8000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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: "Abnormal alpha-synuclein reduces nigral voltage-dependent anion channel 1 in sporadic and experimental Parkinson's disease." dans: Neurobiology of disease, Vol. 69, pp. 1-14, (2014) (PubMed).
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- VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
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Autre désignation
- VDAC1
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Sujet
- VDAC1 forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules, in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. The protein may participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
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Poids moléculaire
- 30773
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ID gène
- 7416
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NCBI Accession
- NP_003365
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UniProt
- P21796
Antigène
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