LAT2 anticorps (AA 30-203)
Aperçu rapide pour LAT2 anticorps (AA 30-203) (ABIN238345)
Antigène
Voir toutes LAT2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 30-203
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Specificité
- This polyclonal antibody reacts with Non-T cell Activation Linker (NTAL), also known as LAB (linker of activated B cells), a 25 kDa transmembrane adaptor protein present in membrane microdomains (rafts) of B cells, NK cells and myeloid cells.
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Purification
- Protein-A Affinity Chromatography
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Immunogène
- Recombinant Mouse NTAL (aa 30-203).
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Indications d'application
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Western Blotting (Non-reducing conditions): Recommended dilution: 1 μg/mLPositive control: mouse spleen. Sample preparation: Mix lysate with non-reducing SDS-PAGE sample buffer. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH ~7.4, 15 mM Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))
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Autre désignation
- LAT2 / WBSCR15
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Sujet
- NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.Synonyms: HSPC046, LAB, LLinker for activation of B-cells, Linker for activation of T-cells family member 2, Membrane-associated adapter molecule, NTAL, Non-T-cell activation linker, WBS15, WBSCR5, Williams-Beuren syndrome chromosomal region 15 protein
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ID gène
- 56743
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NCBI Accession
- NP_064428
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UniProt
- Q9JHL0
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Pathways
- Fc-epsilon Receptor Signaling Pathway, BCR Signaling
Antigène
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