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LAT2 anticorps (AA 30-203)

Cet anticorps Lapin Polyclonal détecte spécifiquement LAT2 dans WB et IF. Il présente une réactivité avec des échantillons de Souris et Rat.
N° du produit ABIN238345
458,46 €
Plus frais de livraison 40,00 € et TVA
0.1 mg
Destination: France
Envoi sous 17 jours ouvrables

Aperçu rapide pour LAT2 anticorps (AA 30-203) (ABIN238345)

Antigène

Voir toutes LAT2 Anticorps
LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Reactivité

  • 60
  • 27
  • 15
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Souris, Rat

Hôte

  • 51
  • 19
  • 1
Lapin

Clonalité

  • 52
  • 19
Polyclonal

Conjugué

  • 53
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp LAT2 est non-conjugé

Application

  • 58
  • 22
  • 20
  • 16
  • 10
  • 8
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Épitope

    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-203

    Specificité

    This polyclonal antibody reacts with Non-T cell Activation Linker (NTAL), also known as LAB (linker of activated B cells), a 25 kDa transmembrane adaptor protein present in membrane microdomains (rafts) of B cells, NK cells and myeloid cells.

    Purification

    Protein-A Affinity Chromatography

    Immunogène

    Recombinant Mouse NTAL (aa 30-203).
  • Indications d'application

    Western Blotting (Non-reducing conditions): Recommended dilution: 1 μg/mLPositive control: mouse spleen. Sample preparation: Mix lysate with non-reducing SDS-PAGE sample buffer. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS, pH ~7.4, 15 mM Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

    Autre désignation

    LAT2 / WBSCR15

    Sujet

    NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.Synonyms: HSPC046, LAB, LLinker for activation of B-cells, Linker for activation of T-cells family member 2, Membrane-associated adapter molecule, NTAL, Non-T-cell activation linker, WBS15, WBSCR5, Williams-Beuren syndrome chromosomal region 15 protein

    ID gène

    56743

    NCBI Accession

    NP_064428

    UniProt

    Q9JHL0

    Pathways

    Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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