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DARPP32 anticorps (pThr75)

Il existe 3+ publications pour ce produit. L’anticorps anti-DARPP32 Polyclonal Lapin est utilisé pour la détection de DARPP32 dans des échantillons de Rat. Il a été validé pour WB et ELISA.
N° du produit ABIN361463
589,60 €
Plus frais de livraison 40,00 € et TVA
100 μL
Destination: France
Envoi sous 7 à 10 jours ouvrables

Aperçu rapide pour DARPP32 anticorps (pThr75) (ABIN361463)

Antigène

Voir toutes DARPP32 (PPP1R1B) Anticorps
DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))

Reactivité

  • 102
  • 95
  • 83
  • 11
  • 10
  • 10
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Rat

Hôte

  • 119
  • 13
  • 1
  • 1
  • 1
Lapin

Clonalité

  • 103
  • 32
Polyclonal

Conjugué

  • 75
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
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  • 2
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  • 2
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  • 1
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Cet anticorp DARPP32 est non-conjugé

Application

  • 104
  • 49
  • 43
  • 28
  • 27
  • 27
  • 14
  • 14
  • 12
  • 8
  • 2
Western Blotting (WB), ELISA
  • Épitope

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    • 15
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    • 2
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    • 1
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    pThr75

    Specificité

    Specific for endogenous levels of the ~32 kDa DARPP-32 protein phosphorylated at Thr75. Immunolabeling is completely eliminated by treatment with λ-phosphatase.

     Réactivité croisée

    Souris, Rat

    Homologie

    bovine, canine, chicken, human, non-human primates

    Attributs du produit

    Our Anti-DARPP-32 (Thr75) Antibody phosphospecific primary antibody is rabbit polyclonal. It detects DARPP-32 (Thr75) and is antigen affinity purified. It is great for use in ELISA, WB.

    Purification

    Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephospho-peptide affinity columns.

    Immunogène

    Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr75 of rat DARPP-32 conjugated to keyhole limpet hemocyanin (KLH).

    Isotype

    IgG
  • Indications d'application

    Dilution Range: WB Brain: 1:1000

    Dilution Range: WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

    Stock

    -20 °C

    Stockage commentaire

    Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

    Date de péremption

    12 months
  • Gomez, Midde, Mactutus, Booze, Zhu: "Environmental enrichment alters nicotine-mediated locomotor sensitization and phosphorylation of DARPP-32 and CREB in rat prefrontal cortex." dans: PLoS ONE, Vol. 7, Issue 8, pp. e44149, (2013) (PubMed).

    Cantrup, Sathanantham, Rushlow, Rajakumar: "Chronic hyperdopaminergic activity of schizophrenia is associated with increased ΔFosB levels and cdk-5 signaling in the nucleus accumbens." dans: Neuroscience, Vol. 222, pp. 124-35, (2012) (PubMed).

    Napolitano, Bonito-Oliva, Federici, Carta, Errico, Magara, Martella, Nistica: "Role of aberrant striatal dopamine D1 receptor/cAMP/protein kinase A/DARPP32 signaling in the paradoxical calming effect of amphetamine." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 33, pp. 11043-56, (2010) (PubMed).

  • Antigène

    DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))

    Autre désignation

    PPP1R1B

    Sujet

    Synonyms: DARPP32 antibody, DARPP-32 antibody, Dopamine and cAMP regulated neuronal phosphoprotein 32 antibody, Dopamine and cAMP regulated neuronal phosphoprotein antibody, Dopamine and cAMP regulated phosphoprotein antibody, Dopamine and cAMP regulated phosphoprotein DARPP 32 antibody, Dopamine and cAMP regulated phosphoprotein DARPP32 antibody, Dopamine- and cAMP-regulated neuronal phosphoprotein antibody, FLJ20940 antibody, IPPD antibody, Neuronal phosphoprotein DARPP 32 antibody, PPP1R1B antibody, PPR1B_HUMAN antibody, Protein phosphatase 1 regulatory (inhibitor) subunit 1B antibody, Protein phosphatase 1 regulatory inhibitor subunit 1B antibody, Protein phosphatase 1 regulatory subunit 1B antibody

    Description Logic: Our Anti-DARPP-32 (Thr75) Antibody phosphospecific primary antibody is rabbit polyclonal. It detects DARPP-32 (Thr75) and is antigen affinity purified. It is great for use in ELISA, WB.

    Gene Name Alternatives: PPP1R1B

    Poids moléculaire

    32 kDa

    ID gène

    360616

    UniProt

    Q6J4I0
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