DARPP32 anticorps (pThr75)
Aperçu rapide pour DARPP32 anticorps (pThr75) (ABIN361463)
Antigène
Voir toutes DARPP32 (PPP1R1B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pThr75
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Specificité
- Specific for endogenous levels of the ~32 kDa DARPP-32 protein phosphorylated at Thr75. Immunolabeling is completely eliminated by treatment with λ-phosphatase.
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Réactivité croisée
- Souris, Rat
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Homologie
- bovine, canine, chicken, human, non-human primates
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Attributs du produit
- Our Anti-DARPP-32 (Thr75) Antibody phosphospecific primary antibody is rabbit polyclonal. It detects DARPP-32 (Thr75) and is antigen affinity purified. It is great for use in ELISA, WB.
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Purification
- Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephospho-peptide affinity columns.
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Immunogène
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr75 of rat DARPP-32 conjugated to keyhole limpet hemocyanin (KLH).
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Isotype
- IgG
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Indications d'application
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Dilution Range: WB Brain: 1:1000
Dilution Range: WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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Stock
- -20 °C
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Stockage commentaire
- Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
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Date de péremption
- 12 months
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: "Environmental enrichment alters nicotine-mediated locomotor sensitization and phosphorylation of DARPP-32 and CREB in rat prefrontal cortex." dans: PLoS ONE, Vol. 7, Issue 8, pp. e44149, (2013) (PubMed).
: "Chronic hyperdopaminergic activity of schizophrenia is associated with increased ΔFosB levels and cdk-5 signaling in the nucleus accumbens." dans: Neuroscience, Vol. 222, pp. 124-35, (2012) (PubMed).
: "Role of aberrant striatal dopamine D1 receptor/cAMP/protein kinase A/DARPP32 signaling in the paradoxical calming effect of amphetamine." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 33, pp. 11043-56, (2010) (PubMed).
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- DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))
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Autre désignation
- PPP1R1B
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Sujet
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Synonyms: DARPP32 antibody, DARPP-32 antibody, Dopamine and cAMP regulated neuronal phosphoprotein 32 antibody, Dopamine and cAMP regulated neuronal phosphoprotein antibody, Dopamine and cAMP regulated phosphoprotein antibody, Dopamine and cAMP regulated phosphoprotein DARPP 32 antibody, Dopamine and cAMP regulated phosphoprotein DARPP32 antibody, Dopamine- and cAMP-regulated neuronal phosphoprotein antibody, FLJ20940 antibody, IPPD antibody, Neuronal phosphoprotein DARPP 32 antibody, PPP1R1B antibody, PPR1B_HUMAN antibody, Protein phosphatase 1 regulatory (inhibitor) subunit 1B antibody, Protein phosphatase 1 regulatory inhibitor subunit 1B antibody, Protein phosphatase 1 regulatory subunit 1B antibody
Description Logic: Our Anti-DARPP-32 (Thr75) Antibody phosphospecific primary antibody is rabbit polyclonal. It detects DARPP-32 (Thr75) and is antigen affinity purified. It is great for use in ELISA, WB.
Gene Name Alternatives: PPP1R1B
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Poids moléculaire
- 32 kDa
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ID gène
- 360616
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UniProt
- Q6J4I0
Antigène
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