VDAC1 anticorps (AA 175-200)
(3 références)
Aperçu rapide pour VDAC1 anticorps (AA 175-200) (ABIN129654)
Antigène
Voir toutes VDAC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 175-200
-
N° du produit (Fournisseur)
- 600-401-882
-
Fournisseur
- Rockland
-
Fonction
- VDAC/Porin Antibody
-
Réactivité croisée (Details)
- Anti-VDAC/Porin Antibody is directed against human VDAC1/Porin1 protein.
-
Attributs du produit
- Synonyms: rabbit anti-VDAC/Porin antibody, VDAC-1 Loading Control Antibody, Porin Loading Control Antibody, VDAC-1 Antibody, VDAC1 Antibody, POR1 Antibody, Porin Antibody, Voltage-dependent anion-selective channel protein 1, Outer mitochondrial membrane protein porin 1
-
Purification
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
-
Stérilité
- Sterile filtered
-
Immunogène
-
Immunogen: VDAC/Porin Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 175-200 of Human VDAC1/Porin1.
Immunogen Type: Conjugated Peptide
-
Isotype
- IgG
-
-
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-30), (N-Term) antibody
VDAC1 Reactivité: Humain, Souris WB, IHC (p), FACS Hôte: Lapin Polyclonal RB19920 unconjugated
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 154-181), (Middle Region) antibodyVDAC1 Reactivité: Humain, Rat, Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Atto 488)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 Atto 488
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Atto 390)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 Atto 390
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Biotin)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 Biotin
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (APC)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 APC
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (PerCP)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 PerCP
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (PE)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 PE
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Atto 594)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 Atto 594
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (FITC)VDAC1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S152B-23 FITC
-
-
Indications d'application
-
Immunohistochemistry Dilution: User Optimized
Application Note: VDAC/Porin Antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band at ~30-33 kDa in size corresponding to VDAC/Porin by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:15,000 - 1:30,000
Other: User Optimized
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1.0 mg/mL
-
Buffer
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store VDAC antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
Date de péremption
- 12 months
-
-
-
: "The transcriptome of mouse central nervous system myelin." dans: Scientific reports, Vol. 6, pp. 25828, (2018) (PubMed).
: "Impact of Rac1 and Cdc42 signaling during early herpes simplex virus type 1 infection of keratinocytes." dans: Journal of virology, Vol. 83, Issue 19, pp. 9759-72, (2009) (PubMed).
: "Intraarterial thrombolytic therapy within 3 hours of the onset of stroke." dans: Neurosurgery, Vol. 54, Issue 1, pp. 39-44; discussion 44-6, (2003) (PubMed).
-
-
- VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
-
Autre désignation
- VDAC1
-
Sujet
- Background: VDAC/Porin Antibody recognizes VDAC (also known as Voltage-dependent anion-selective channel protein 1, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL) which is an outer membrane mitochondrial protein. The VDAC proteins are ~30-33 kDa (some isoforms are larger - see below). The VDAC proteins are thought to form aqueous channels, or pores, through which adenine nucleotides cross the outer mitochondrial membrane. VDACs have been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, adenine nucleotide translocator (ANT), and cyclophilin D (CypD), is thought to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis. VDACs are highly expressed in heart, liver and skeletal muscle, where concentrations of mitochondria are at their highest. This antibody can be used as a loading control with whole cell lysates and total mitochondrial preparations.
-
ID gène
- 7416
-
NCBI Accession
- NP_003365
-
UniProt
- P21796
Antigène
-
