L-Selectin anticorps
Aperçu rapide pour L-Selectin anticorps (ABIN135253)
Antigène
Voir toutes L-Selectin (SELL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Rat Anti-Mouse CD62L-LE/AF
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Specificité
- Mouse CD62L, Mr 74 kDa on lymphocytes and Mr 95 kDa on neutrophils
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Attributs du produit
- Low Endotoxin/Azide Free Anti-Mouse CD62L antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, blocking, and cytotoxicity assays.
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niveau d'endotoxine
- Low Endotoxin
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Immunogène
- C3H/eb cloned mouse B cell lymphoma 38C-13
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate buffered saline, pH 7.4
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Agent conservateur
- Azide free
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Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C
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- L-Selectin (SELL) (Selectin L (SELL))
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Autre désignation
- CD62L
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Sujet
- CD62L, also known as L-selectin, is a type I transmembrane glycoprotein with lectin-like and Epidermal Growth Factor-like domains. It binds to sialylated oligosaccharide determinants on high endothelial venules (HEV) in peripheral lymph nodes. In the mouse, CD62L is expressed on most thymocytes and on peripheral leukocytes, including B and T lymphocytes, neutrophils, monocytes and eosinophils. This member of the selectin family of cell adhesion molecules appears to be required for lymphocyte homing to peripheral lymph nodes and for leukocyte extravasation at sites of inflammation. Expression of CD62L on lymphocytes and neutrophils is rapidly down-regulated upon cell activation and the level of CD62L expression, along with other markers, distinguishes naive T cells from effector/memory T cells.
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ID gène
- 20343
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UniProt
- P18337
Antigène
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