MONTRER AIDE VIDEOMontrer la vidéo expliquant commment utiliser le moteur de recherche
(Flash nécessaire) Show Tutorial VideoMontrer la vidéo expliquant commment utiliser le moteur de recherche
(Flash nécessaire)
Détail du produit

anti-CEACAM5 (CEA, CD66e) anticorps

Aperçu

Image pour anti-CEACAM5 (CEA, CD66e) anticorps
Antigène: CEACAM5 (CEA, CD66e)
Clonalité: Monoclonal (26-3-13)
Application: Flow Cytometry (FACS), Cell-ELISA (cELISA), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Reactivité: Human
Hôte: Mouse
9 références disponible 9 références disponible
Quantité: 100 ug (1mg/ml)
Prix: 551,31 $   (Plus frais de livraison $25 et TVA, Invoice in EUR)
Numéro du produit: ABIN108727
Disponibilité: Envoi sous 1 à 2 jours
Comment commander Comment commander
Ajouter au panier

sur cette page

Description du produit
Applications
Références
Images
Produits apparentés

Service clientèle

Poser une question technique
Envoyer les détails du produit à un collègue
Télécharger la fiche technique

Description du produit  » anti-CEACAM5 (CEA, CD66e) anticorps

Haut de la page ^


Antigène CEACAM5 (CEA, CD66e)
Immunogène Immunisation with extracted protein of CEACAM5
Reactivité Human
Clonalité Monoclonal
Format Purified
Isotype IgG1 »Anticorps secondaires correspondants
Description CEACAM5 (CEA-related cell adhesion molecule 5, CEA) belongs to the carcinoembryonic antigen (CEA) gene family (5). It encodes a glycosyl phosphatidylinositol (GPI)- linked glycoprotein with a Mr of 180,000-200,000 which is most strongly expressed on epithelial cells of the fetal and adult colon and to a minor extent on epithelial cells of the stomach and sweat glands, squamous epithelial cell of the tongue, esophagus and cervix. CEACAM5 is used as a tumor marker for early detection of recurrent disease due its expression in adenocarcinomas of the colon, lung, breast, stomach and pancreas and in mucinous ovarian carcinomas (5). Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3).
Clone 26-3-13
Hôte Mouse
Specificité Anti-human CEACAM5 (CEA, CD66e)

Applications  » anti-CEACAM5 (CEA, CD66e) anticorps

Haut de la page ^


Application Flow Cytometry (FACS), Cell-ELISA (cELISA), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Indications d'application Flow cytometry: 1.2 ug/10^6 cells. ELISA: 1:200 - 1:400 CELISA: 1:200. Western blot: 4ug/ml. Immunohistology: 1-2 ug/10^6 cells (on cryosections)
Concentration 1mg/ml
Purification Protein G
Buffer Phosphate buffered saline, pH 7.2
Stock Short term: 2°C - 8°C. Long term: -20°C (avoid repeated freezing and thawing)
Domaine de recherche Receptors, Cancer, Receptors, Cell/Tissue Markers, Cancer
Restrictions For Research Use only

Références  » anti-CEACAM5 (CEA, CD66e) anticorps

Haut de la page ^


Références Strobel, Strobel, Bross et al.: "Effects of human bone marrow stroma on the growth of human tumor cells." In: Cancer research , Vol. 49, Issue 4, pp. 1001-7, 1989 (PubMed)

Grunert, AbuHarfeil, Schwarz et al.: "Two CEA and three NCA species, although distinguishable by monoclonal antibodies, have nearly identical peptide patterns." In: International journal of cancer. Journal international du cancer , Vol. 36, Issue 3, pp. 357-62, 1985 (PubMed)

Thompson, Moessinger, Reichardt et al.: "A polymerase-chain-reaction assay for the specific identification of transcripts encoded by individual carcinoembryonic antigen (CEA)-gene-family members." In: International journal of cancer. Journal international du cancer , Vol. 55, Issue 2, pp. 311-9, 1993 (PubMed)

Krop-Watorek, Laskowska, Salwa et al.: "CEA-related proteins on human urothelial cell lines of different transformation grades." In: Cancer letters , Vol. 139, Issue 1, pp. 15-22, 1999 (PubMed)

Schoelzel, Zimmermann, Schwarzkopf et al.: "Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas." In: The American journal of pathology , Vol. 156, Issue 2, pp. 595-605, 2000 (PubMed)

Baczy?ska, Wietrzyk, Madej et al.: "The tumorigenic potential of human CX-1 colon adenocarcinoma cells depends on carcinoembryonic antigen (CEACAM5) expression." In: Cellular & molecular biology letters , Vol. 8, Issue 2, pp. 471-86, 2003 (PubMed)

Schmitter, Agerer, Peterson et al.: "Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens." In: The Journal of experimental medicine , Vol. 199, Issue 1, pp. 35-46, 2004 (PubMed)

Kammerer, Riesenberg, Weiler et al.: "The tumour suppressor gene CEACAM1 is completely but reversibly downregulated in renal cell carcinoma." In: The Journal of pathology , Vol. 204, Issue 3, pp. 258-67, 2004 (PubMed)

Noeckel, van den Engel, Winter et al.: "Characterization of gastric adenocarcinoma cell lines established from CEA424/SV40 T antigen-transgenic mice with or without a human CEA transgene." In: BMC cancer , Vol. 6, pp. 57, 2006 (PubMed)