Smooth Muscle Actin anticorps (N-Term)

N° du produit ABIN114404

L’anticorps anti-Smooth Muscle Actin Monoclonal Souris est utilisé pour la détection de Smooth Muscle Actin dans des échantillons de Humain, Rat, Souris, Poulet, Lapin et Boeuf (Vache). Il a été validé pour IHC (p).

Aperçu rapide pour Smooth Muscle Actin anticorps (N-Term) (ABIN114404)

Antigène: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reactivité: Humain, Rat, Souris, Poulet, Lapin, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Smooth Muscle Actin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1A4-asm-1

Détail du produit anti-Smooth Muscle Actin anticorps

Épitope: N-Term

Specificité: This antibody is specific to alpha-smooth isoform of actin. It reacts with smooth muscle cells of vessels and different parenchymes. The antibody does not cross-react with beta and gamma-cytoplasmic, alpha-sarcomeric and alpha-myocardial actin isoforms.
Cellular Localization: Cytoplasmic.

Purification: Purified

Immunogène: N-terminal decapeptide of alpha-smooth muscle Actin

Isotype: IgG2a

Information d'application

Indications d'application: Immunohistochemistry on Formalin Fixed Paraffin Embedded Sections: Use Actin antibodyat 1/25-1/50 dilution in an ABC method for 30 minutes at room temperature. Recommended Positive Control: Leiomyoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Smooth Muscle Actin

Antigène: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Sujet: Smooth muscle actin is expressed in normal smooth muscle and in myoepithelial cells, and also in tumours derived from these cells. Actins are involved in maintaining the structure and integrity of a cell, as well as cell motility. They are highly conserved proteins and make up the majority of the contractile apparatus. To date, six different actin isoforms have been described.Synonyms: ACTSA, ACTVS, Alpha-actin-2, Cell growth-inhibiting gene 46 protein

ID gène: 59

NCBI Accession: NP_001135417

UniProt: P62736

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development