Smooth Muscle Actin anticorps (N-Term)

N° du produit ABIN185271

Cité dans 5 publications. Cet anticorps anti-Smooth Muscle Actin Polyclonal Chèvre (ABIN185271) détecte spécifiquement Smooth Muscle Actin dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Smooth Muscle Actin anticorps (N-Term) (ABIN185271)

Antigène: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reactivité: Humain, Rat, Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Smooth Muscle Actin est non-conjugé

Application: Western Blotting (WB), ELISA

Classe de qualité: Verified

Détail du produit anti-Smooth Muscle Actin anticorps

Épitope: N-Term

Fonction: Smooth muscle alpha-actin

Séquence: EEEDSTALVC

Specificité: Variants NP_001604.1 and NP_001135417.1 encode the same protein.

Réactivité croisée: Chien, Humain, Souris, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogène: Peptide with sequence EEEDSTALVC, from the N Terminus of the protein sequence according to NP_001604.1, NP_001135417.1.

Isotype: IgG

Information d'application

Indications d'application:

Western Blot: Approx 42 kDa band observed in Human Heart, Mouse Duodenum and in lysates of cell lines HeLa and NIH3T3, and approx. 45 kDa in Rat Heart lysates (calculated MW of 42 kDa according to Human NP_001604, Mouse NP_031418.1 and Rat NP_112266.1). R

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Références pour anticorps anti-Smooth Muscle Actin (ABIN185271)

Cunha, Leuckx, Sterkendries, Korf, Bomfim-Ferreira, Overbergh, Vaes, Heimberg, Gysemans, Mathieu: "Human multipotent adult progenitor cells enhance islet function and revascularisation when co-transplanted as a composite pellet in a mouse model of diabetes." dans: Diabetologia, Vol. 60, Issue 1, pp. 134-142, (2017) (PubMed).

Nischalke, Berger, Lutz, Langhans, Wolter, Eisenhardt, Krämer, Kokordelis, Glässner, Müller, Rosendahl, Fischer, Berg, Grünhage, Leifeld, Soyka, Nattermann, Sauerbruch, Stickel, Spengler: "Influence of the CXCL1 rs4074 A allele on alcohol induced cirrhosis and HCC in patients of European descent." dans: PLoS ONE, Vol. 8, Issue 11, pp. e80848, (2014) (PubMed).

Park, Chen, Hoffman, Marsh, West, Grunig: "Modification of hemodynamic and immune responses to exposure with a weak antigen by the expression of a hypomorphic BMPR2 gene." dans: PLoS ONE, Vol. 8, Issue 1, pp. e55180, (2013) (PubMed).

Trokovic, Pöllänen, Porola, Stegaev, Hetzel, Tivesten, Engdahl, Carlsten, Forsblad-dElia, Fagman, Lagerquist, Konttinen: "Exosomal secretion of death bullets: a new way of apoptotic escape?" dans: American journal of physiology. Endocrinology and metabolism, Vol. 303, Issue 8, pp. E1015-24, (2012) (PubMed).

McIntire, Sifers, Platt, Ganacias, Langat, Hunt: "Novel HLA-G-binding leukocyte immunoglobulin-like receptor (LILR) expression patterns in human placentas and umbilical cords." dans: Placenta, Vol. 29, Issue 7, pp. 631-8, (2008) (PubMed).

Détails sur Smooth Muscle Actin

Antigène: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Autre désignation: ACTA2

Sujet: ACTA2, actin, alpha 2, smooth muscle, aorta, OTTHUMP00000020042, ACTSA, AAT6, ACTSA, alpha 2 actin, alpha-cardiac actin, growth-inhibiting gene 46, smooth muscle alpha-actin,

ID gène: 59

NCBI Accession: NP_001604, NP_001135417

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development