HSP90AB1 anticorps (N-Term)

N° du produit ABIN343707

Cet anticorps anti-HSP90AB1 Monoclonal Souris (Clone MBH90B) (ABIN343707) détecte spécifiquement HSP90AB1 dans WB, IP et ICC. L’anticorps est réactif avec des échantillons de Humain, Souris et Boeuf (Vache).

Aperçu rapide pour HSP90AB1 anticorps (N-Term) (ABIN343707)

Antigène: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Reactivité: Humain, Souris, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSP90AB1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: MBH90B

Détail du produit anti-HSP90AB1 anticorps

Épitope: N-Term

Fonction: Anti-HSP90 beta Purified

Réactivité croisée (Details): Human, Mouse, Bovine, Other not determined

Attributs du produit: The antibody MBH90B recognizes the EEVHHG epitope within the N-terminal part of Hsp90 beta an ubiquitously expressed intracellular protein with calculated Mw of 83.3 kDa, however, migrating as a 90 kDa band under reducing SDS-PAGE conditions.

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Peptide corresponding to the EEVHHGEEEVEC sequence within N-terminal part of human Hsp90.

Isotype: IgG1

Information d'application

Indications d'application: Western blotting: Recommended dilution: 1 μg/mL.
Immunocytochemistry: Recommended dilution: 1 μg/mL.
Immunoprecipitation: Recommended dilution: 1 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur HSP90AB1

Antigène: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Autre désignation: HSP90 beta

Sujet: Heat shock protein 90 beta,Hsp90 beta (heat shock protein 90 beta) is a constitutively expressed isoform of Hsp90, one of the most abundant chaperones in the cytosol of eukaryotic cells. Hsp90 interacts with various proteins, including protein kinases and transcription factors, and either facilitates their stabilization and activation or directs them for proteasomal degradation. Hsp90 thus affects multiple signaling pathways and biological processes and modulation of this single target offers the prospect of simultaneous intervence to various key points of oncogenic transformation. Hsp90 operates as a dimer in a conformational cycle driven by ATP binding and hydrolysis.,HSP90B, HSPCB

ID gène: 35

UniProt: P08238

Pathways: Regulation of Cell Size