GRIN1/NMDAR1 anticorps (AA 1-564)

N° du produit ABIN361405

Cet anticorps Souris Monoclonal détecte spécifiquement GRIN1/NMDAR1 dans WB, IHC, ELISA et ICC. Il présente une réactivité avec des échantillons de Rat. Il a été cité dans 4+ publications.

Aperçu rapide pour GRIN1/NMDAR1 anticorps (AA 1-564) (ABIN361405)

Antigène: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GRIN1/NMDAR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: R1JHL

Détail du produit anti-GRIN1/NMDAR1 anticorps

Épitope: AA 1-564

Specificité: Specific for endogenous levels of the ~120 kDa NR1 subunit of the NMDA receptor.

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Our Anti-NMDA NR1 Subunit Antibody primary antibody is mouse monoclonal. It detects human, mouse, and rat NMDA NR1 Subunit and is culture supernatant. It is great for use in ELISA, WB, IHC, ICC.

Purification: Culture supernatant.

Immunogène: Fusion protein containing amino acids 1-564 of the NR1 subunit of rat NMDA receptor.

Isotype: IgG

Information d'application

Indications d'application:

Dilution Range: IP: 3 μg per 200 μg lysate

Dilution Range: ICC: 1:10

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Reconstitute in 50 μl phosphate buffered saline (PBS: 137 mM NaCl, 7.5 mM Na2HPO4, 2.7 mM KCl, 1.5 mM KH2PO4, pH 7.4) before use. After reconstitution it is recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Date de péremption: 12 months

Références pour anticorps anti-GRIN1/NMDAR1 (ABIN361405)

Quillinan, Grewal, Deng, Shimizu, Yonchek, Strnad, Traystman, Herson: "Region-specific role for GluN2B-containing NMDA receptors in injury to Purkinje cells and CA1 neurons following global cerebral ischemia." dans: Neuroscience, Vol. 284, pp. 555-65, (2014) (PubMed).

Hicklin, Wu, Radcliffe, Freund, Goebel-Goody, Correa, Proctor, Lombroso, Browning: "Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 16, pp. 6650-5, (2011) (PubMed).

Davies, Goebel-Goody, Coultrap, Browning: "Long term synaptic depression that is associated with GluR1 dephosphorylation but not alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization." dans: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33138-46, (2008) (PubMed).

Zhang, Dong, Zhang, Ichinose, Wu, Culley, Crosby, Tanzi, Xie: "Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 17, pp. 4551-60, (2008) (PubMed).

Détails sur GRIN1/NMDAR1

Antigène: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Autre désignation: GRIN1

Sujet:

Synonyms: GluN1 antibody, Glutamate [NMDA] receptor subunit zeta-1 antibody, Glutamate receptor ionotropic N methyl D aspartate 1 antibody, Glutamate receptor ionotropic N-methyl-D aspartate subunit 1 antibody, glutamate receptor ionotropic NMDA 1 antibody, Grin1 antibody, MRD8 antibody, N methyl D aspartate receptor antibody, N methyl D aspartate receptor channel subunit zeta 1 antibody, N methyl D aspartate receptor subunit NR1 antibody, N-methyl-D-aspartate receptor subunit NR1 antibody, NMD-R1 antibody, NMDA 1 antibody, NMDA R1 antibody, NMDAR1 antibody, NMDA receptor 1 antibody, NMDA1 antibody, NMDAR antibody, NMDZ1_HUMAN antibody, NR1 antibody

Description Logic: Our Anti-NMDA NR1 Subunit Antibody primary antibody is mouse monoclonal. It detects human, mouse, and rat NMDA NR1 Subunit and is culture supernatant. It is great for use in ELISA, WB, IHC, ICC.

Gene Name Alternatives: GRIN1

Poids moléculaire: 120 kDa

ID gène: 24408

UniProt: P35439

Pathways: Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity