ARL6 Protein (AA 1-186) (His tag)

N° du produit ABIN7676507

Protéine Recombinant ARL6 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour ARL6 Protein (AA 1-186) (His tag) (ABIN7676507)

Antigène: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 90 %

Détail du produit

Attributs du protein: AA 1-186

Purification/Conjugué: Cette ARL6 protéine est marqué à la His tag.

Séquence: MGLLDRLSVL LGLKKKEVHV LCLGLDNSGK TTIINKLKPS NAQSQNILPT IGFSIEKFKS SSLSFTVFDM SGQGRYRNLW EHYYKEGQAI IFVIDSSDRL RMVVAKEELD TLLNHPDIKH RRIPILFFAN KMDLRDAVTS VKVSQLLCLE NIKDKPWHIC ASDAIKGEGL QEGVDWLQDQ IQTVKT

Attributs du produit: ARL6, 1-186aa, Human, His tag, E.coli

Purification: > 90% by SDS-PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 20 % glycerol, 0.2M NaCl,5 mM DTT

Conseil sur la manipulation: Avoid repeated freezing and thawing cycles

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Autre désignation: BBS3/ARL6

Sujet: ARL6, also known ADP-ribosylation factor-like protein 6, belongs to the ARF family of GTP-binding proteins. This protein is known to play essential roles in modulating membrane trafficking and cytoskeletal functions. Mutation in ARL6 causes Bardet-Biedl syndrome (BBS3). BBS is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnor-malities and developmental delay. Recombinant human ARL6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Poids moléculaire: 23.2 kDa (206aa) confirmed by MALDI-TOF

NCBI Accession: NP_115522