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2B4 Produits

(Natural Killer Cell Receptor 2B4 (CD244))
This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].

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Catégories 2B4 en vedette

2B4 Anticorps

High quality antibodies with extensive validation data.

2B4 Kits ELISA

Reliable ELISA kits for a wide range of species.

2B4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

2B4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7441829
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, FACS
Validations
  • (5)
N° du produit ABIN6964066
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (4)
N° du produit ABIN6260596
Quantité 100 μL
Fiche technique Fiche technique

2B4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965553
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1672841
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6720218
Quantité 1 kit
Fiche technique Fiche technique

2B4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7273780
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7273781
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7273782
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits 2B4

Peiffer, Wang, Zimmerman, Ransom, Carmella, Kuo, Chen, Oshima, Huang, Hecht, Stoner: "Dietary Consumption of Black Raspberries or Their Anthocyanin Constituents Alters Innate Immune Cell Trafficking in Esophageal Cancer." dans: Cancer immunology research, Vol. 4, Issue 1, pp. 72-82, (2016) (PubMed).

Mattiola, Pesant, Tentorio, Molgora, Marcenaro, Lugli, Locati, Mavilio: "Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2818-28, (2015) (PubMed).

Bengsch, Martin, Thimme: "Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation." dans: Journal of hepatology, Vol. 61, Issue 6, pp. 1212-9, (2014) (PubMed).

Kis-Toth, Tsokos: "Engagement of SLAMF2/CD48 prolongs the time frame of effective T cell activation by supporting mature dendritic cell survival." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 9, pp. 4436-42, (2014) (PubMed).

Raziorrouh, Schraut, Gerlach, Nowack, Grüner, Ulsenheimer, Zachoval, Wächtler, Spannagl, Haas, Diepolder, Jung: "The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function." dans: Hepatology (Baltimore, Md.), Vol. 52, Issue 6, pp. 1934-47, (2010) (PubMed).

Fasth, Dastmalchi, Rahbar, Salomonsson, Pandya, Lindroos, Nennesmo, Malmberg, Söderberg-Nauclér, Trollmo, Lundberg, Malmström: "T cell infiltrates in the muscles of patients with dermatomyositis and polymyositis are dominated by CD28null T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 7, pp. 4792-9, (2009) (PubMed).

Cao, Wagers, Karsunky, Zhao, Reeves, Wong, Stevenson, Weissman, Contag: "Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors." dans: Blood, Vol. 112, Issue 12, pp. 4494-502, (2008) (PubMed).

Wahle, Paraiso, Kendig, Lawrence, Chen, Wu, Kerr: "Inappropriate recruitment and activity by the Src homology region 2 domain-containing phosphatase 1 (SHP1) is responsible for receptor dominance in the SHIP-deficient NK cell." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 12, pp. 8009-15, (2007) (PubMed).

Roda-Navarro, Vales-Gomez, Chisholm, Reyburn: "Transfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic function." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 30, pp. 11258-63, (2006) (PubMed).

Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à 2B4

CD244 molecule (CD244), CD244 molecule (Cd244), CD244 natural killer cell receptor 2B4 (Cd244), 2B4, C9.1, CD244, F730046O15Rik, Ly90, NAIL, NKR2B4, Nmrk, SLAMF4

Protein level used designations for 2B4

  • CD244 molecule, natural killer cell receptor 2B4
  • natural killer cell receptor 2B4
  • NK cell activation inducing ligand NAIL
  • NK cell activation-inducing ligand
  • NK cell type I receptor protein 2B4
  • SLAM family member 4
  • h2B4
  • signaling lymphocytic activation molecule 4
  • CD244 natural killer cell receptor 2B4
  • NKR2B4
  • non MHC restricted killing associated
  • non-MHC restricted killing associated
  • transmembrane NK cell receptor 2B4
  • NK cell receptor 2B4
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