anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Anticorps

NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. De plus, nous expédions NQO1 Kits (33) et NQO1 Protéines (14) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
NQO1 1728 P15559
NQO1 24314 P05982
NQO1 18104 Q64669
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Top anti-NQO1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 211 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 2 to 3 Days
$275.00
Détails
Chien Souris Inconjugué FACS, ICC, IF, IHC, IHC (fro), IHC (p), IP, SimWes, WB Detection of NQO1 in A549 lysates using ABIN152344.  Lane 1: 0.5 ug/ml.  Lane 2: 2 ug/ml. Exposure: 1 second. Simple Western: NQO-1 Antibody (A180) [ABIN152344] - Simple Western lane view shows a specific band for NQO-1 in 0.5 mg/ml of A431 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$488.73
Détails
Humain Chèvre Inconjugué ELISA, IF, IHC, WB ABIN184714 staining (0.03µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$429.84
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-NQO1 AntibodyTitration: 1.0 µg/mL  Positive Control: 721_B Whole Cell  There is BioGPS gene expression data showing that NQO1 is expressed in 721_B 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: NQO1 Antibody [NBP1-85223] - Staining of human cell line U-2 OS shows positivity in cytoplasm. Immunohistochemistry-Paraffin: NQO1 Antibody [NBP1-85223] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Lapin Inconjugué WB Anti- NQO1 Picoband antibody, Western blotting All lanes: Anti NQO1  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: Rat Lung Tissue Lysate at 50ug Lane 3: HELA Whole Cell Lysate at 40ug Lane 4: A549 Whole Cell Lysate at 40ug Lane 5: MM231 Whole Cell Lysate at 40ug Lane 6: SW620 Whole Cell Lysate at 40ug Lane 7: 22RV1 Whole Cell Lysate at 40ug Predicted bind size: 31KD Observed bind size: 31KD 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NQO1, antibody at 1:200 dilution. WB Image NQO1 antibody [C2C3], C-term detects NQO1 protein by Western blot analysis. A. 50 µg rat heart lysate/extract 12 % SDS-PAGE NQO1 antibody [C2C3], C-term , dilution: 1:500 100 μL Connectez-vous pour afficher 3 to 4 Days
$466.18
Détails
Chien Chèvre Inconjugué ELISA, WB ABIN249473 staining (1ug/ml) of Human Lung lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence ABIN249473 staining (0.5µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$488.73
Détails
Humain Souris Inconjugué ELISA, IF, IP, WB Immunofluorescence of monoclonal antibody to NQO1 on HepG2 cell (antibody concentration 10 µg/mL). Western blot analysis of NQO1 over-expressed 293 cell line, cotransfected with NQO1 Validated Chimera RNAi used as specificity and loading control. 100 μg Connectez-vous pour afficher 8 to 11 Days
$527.50
Détails

anti-NQO1 Anticorps mieux référencés

  1. Dog (Canine) Monoclonal NQO1 Primary Antibody pour FACS, ICC - ABIN152344 : Siegel, Franklin, Ross: Immunohistochemical detection of NAD(P)H:quinone oxidoreductase in human lung and lung tumors. dans Clinical cancer research : an official journal of the American Association for Cancer Research 1998 (PubMed)
    Show all 29 Pubmed References

  2. Human Polyclonal NQO1 Primary Antibody pour ICC, IF - ABIN4340592 : Heitz, Erb, Anklin, Robay, Pernet, Gueven: Idebenone protects against retinal damage and loss of vision in a mouse model of Leber's hereditary optic neuropathy. dans PLoS ONE 2012 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal NQO1 Primary Antibody pour IF (p), IHC (p) - ABIN678428 : Wang, Peng, Wei, Wei, Wang, Ma, Yao, Fu, Zu: Geraniin exerts cytoprotective effect against cellular oxidative stress by upregulation of Nrf2-mediated antioxidant enzyme expression via PI3K/AKT and ERK1/2 pathway. dans Biochimica et biophysica acta 2015 (PubMed)
    Show all 3 Pubmed References

  4. Dog (Canine) Polyclonal NQO1 Primary Antibody pour ELISA, WB - ABIN249473 : Singh, Zahid, Saeed, Gaikwad, Meza, Cavalieri, Rogan, Chakravarti: NAD(P)H:quinone oxidoreductase 1 Arg139Trp and Pro187Ser polymorphisms imbalance estrogen metabolism towards DNA adduct formation in human mammary epithelial cells. dans The Journal of steroid biochemistry and molecular biology 2009 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal NQO1 Primary Antibody pour IHC (p), IP - ABIN2475931 : Honda: [Status of emergencies and their transport system in Tokyo]. dans [Kango gijutsu] : [Nursing technique] 1975 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal NQO1 Primary Antibody pour FACS, ELISA - ABIN969320 : Kansanen, Jyrkkänen, Volger, Leinonen, Kivelä, Häkkinen, Woodcock, Schopfer, Horrevoets, Ylä-Herttuala, Freeman, Levonen: Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid. dans The Journal of biological chemistry 2009 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal NQO1 Primary Antibody pour FACS, IHC - ABIN969319 : Douglas, Lim, Porter, West, Pink, Ge, Wylie, Tibbits, Biggs, Curtis, Palombella, Adams, Fritz, Normant: The antiproliferative activity of the heat shock protein 90 inhibitor IPI-504 is not dependent on NAD(P)H:quinone oxidoreductase 1 activity in vivo. dans Molecular cancer therapeutics 2009 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal NQO1 Primary Antibody pour ELISA, WB - ABIN546821 : Asher, Lotem, Kama, Sachs, Shaul: NQO1 stabilizes p53 through a distinct pathway. dans Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

  9. Human Polyclonal NQO1 Primary Antibody pour WB - ABIN1686087 : La Sala, Pujadas, De Nigris, Canivell, Novials, Genovese, Ceriello: Oscillating glucose and constant high glucose induce endoglin expression in endothelial cells: the role of oxidative stress. dans Acta diabetologica 2014 (PubMed)

  10. Human Polyclonal NQO1 Primary Antibody pour ICC, IF - ABIN441361 : Oh, Kim, Kim, Kim, Lee, Hong, Goodwin, Ruthenborg, Jung, Lee, Lee, Park, Kim, Park: NQO1 inhibits proteasome-mediated degradation of HIF-1α. dans Nature communications 2016 (PubMed)

Plus d’anticorps contre NQO1 partenaires d’interaction

Zebrafish NAD(P)H Dehydrogenase, Quinone 1 (NQO1) interaction partners

  1. Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt and JNK/Nrf2/NQO1 pathway.

Human NAD(P)H Dehydrogenase, Quinone 1 (NQO1) interaction partners

  1. functional perturbation analyses at cancer-associated P187 and K240 sites of the multifunctional NADP(H):quinone oxidoreductase 1

  2. NQO1 is a FAD-dependent, two-domain multifunctional stress protein acting as a Phase II enzyme, activating cancer pro-drugs and stabilizing p53 and p73a oncosuppressors.tructural protein:protein interaction studies reveal that the cancer-associated polymorphism does not abolish the interaction with p73alpha, indicating that oncosuppressor destabilization largely mirrors the low intracellular stability of p.P187S.

  3. Inflammation, oxidative stress, and higher expression levels of Nrf2 and NQO1 proteins in the airways of women chronically exposed to biomass fuel smoke.

  4. NQO1 directly binds to the oxygen-dependent domain of HIF-1alpha and inhibits the proteasome-mediated degradation of HIF-1alpha by preventing PHDs from interacting with HIF-1alpha.

  5. Our genetic susceptibility study suggests that the NQO1 wild homozygous is likely to be the susceptible genotype. It means that low dose exposure to benzene (concentration under 0.6 mg/m3) can still cause health hazards to workers, and those workers with NQO1 wild homozygous genotypes were more susceptible than others.

  6. Although the NQO1 rs1800566 variant may not have an effect on risk of pre-eclampsia (PE) in Chinese Han women, further studies of other loci are necessary to clarify the exact role of NQO1 in the pathogenesis of PE.

  7. results obtained here support a previously unrecognized molecular link between polycystic ovary syndrome and endometrial cancer involving NQO1.

  8. In human colonic epithelial cells, significant upregulation of NAD(P)H dehydrogenase [quinone] 1 (up to threefold) and thioredoxin reductase 1 (up to twofold) by 10muM sulforaphane (from broccoli), 5muM carnosol (rosemary), and 20muM cinnamaldehyde (cinnamon) was observed.

  9. Hydrogen sulfide attenuates vascular smooth muscle cell calcification in vitro via the KEAP1-NRF2 redox sensing/stress response system by enhancing NQO1 expression.

  10. the NRF2 target NAD(P)H:quinone oxidoreductase 1 (NQO1) was investigated as a readout parameter for NRF2 activity in monocytes of chronic kidney disease patients (n = 63) compared to those of healthy controls.

  11. NQO1 is a potential drug target for host directed therapy for tuberculosis.

  12. These results indicate that dual-negative expression of Nrf2 and NQO1 is predictive of a better prognosis in NSCLC patients.

  13. Case-control study found a significant difference was observed between large artery atherosclerotic ischemic stroke patients and controls with respect to the CYP2E1*5B genotype and allele distribution. NQO1*2 polymorphism genotype distribution was significantly different between patients and controls and heterozygote *1*2 genotype was found to be a protective factor against large artery atherosclerotic ischemic stroke.

  14. the NQO1 Pro187Ser or SULT1A1 Arg213His polymorphism combination with smoking significantly confer susceptibility to BC. [META-ANALYSIS]

  15. Docosahexaenoic acid (DHA) activates Nrf2, possibly through modification of critical Keap1 cysteine 288 residue and PKCdelta-mediated phosphorylation of Nrf2, leading to upregulation of HO-1 and NQO1 expression.

  16. the upregulation of Cav1 contributed to the DHA-mediated p53 activation and the downregulation of the redox enzyme, NAD(P)H:quinone oxidoreductase 1 (NQO1), which have been reported to contribute to the activation of the cell death pathway.

  17. NQO1 may act as a redox-dependent switch where the protein responds to the NAD(P)+/NAD(P)H redox environment by altering its structure promoting the binding or dissociation of NQO1 with target macromolecules

  18. Taken together, we proposed that NQO1 could potentiate NSCLC cell proliferation by enhancing cellular glycometabolism, and HKII is a key mediator of this mechanism.

  19. The higher incidence of NQO1 mutants among bronchopulmonary dysplasia (BPD) neonates as well as the presence of the mutant allele in all neonates with <= 1,000 g who developed BPD provided the first evidence for a possible pathogenetic role of the C(609)T polymorphism in BPD susceptibility due to the reduction or loss of NQO1 enzymatic activity.

  20. Activity of the enzyme NQO1 does not appear to be developmentally regulated, with levels of hepatic activity as high in neonates and children as they are in adults. Obesity may increase hepatic NQO1 activity in children.

Pig (Porcine) NAD(P)H Dehydrogenase, Quinone 1 (NQO1) interaction partners

  1. The obtained data convincingly showed that porcine NADPH-d cells may produce nitric oxide.

  2. Immunoreactivity of eNOS was similar to NADPH-d staining. Clear iNOS immunoreactivity was detected in the luminal epithelium, endometrial stroma and individual endometrial glands.

Cow (Bovine) NAD(P)H Dehydrogenase, Quinone 1 (NQO1) interaction partners

  1. NQO1 expression was increased in the ruminal papillae of more efficient low residual feed intake (RFI) animals compared to the high RFI animals

NQO1 profil antigène

Profil protéine

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with NQO1

  • NAD(P)H dehydrogenase, quinone 1 (nqo1) anticorps
  • NAD(P)H quinone dehydrogenase 1 (NQO1) anticorps
  • NAD(P)H dehydrogenase, quinone 1 (Bpet2092) anticorps
  • NAD(P)H dehydrogenase, quinone 1 L homeolog (nqo1.L) anticorps
  • NAD(P)H quinone dehydrogenase 1 (nqo1) anticorps
  • NAD(P)H quinone dehydrogenase 1 (Nqo1) anticorps
  • NAD(P)H dehydrogenase, quinone 1 (Nqo1) anticorps
  • AV001255 anticorps
  • DHQU anticorps
  • Dia4 anticorps
  • Dtd anticorps
  • NADPH-d anticorps
  • Nmo-1 anticorps
  • Nmo1 anticorps
  • Nmor1 anticorps
  • NMORI anticorps
  • nqo1 anticorps
  • Ox-1 anticorps
  • Ox1 anticorps
  • Qr1 anticorps
  • wu:fb63c10 anticorps
  • zgc:77191 anticorps

Protein level used designations for NQO1

NAD(P)H dehydrogenase [quinone] 1 , NAD(P)H menadione oxidoreductase 1, dioxin-inducible , NAD(P)H dehydrogenase, quinone 1 , DT-diaphorase , DTD , NAD(P)H:quinone oxidoreductase 1 , QR1 , azoreductase , menadione reductase , phylloquinone reductase , quinone reductase 1 , nad(p)h dehydrogenase (quinone) 1 , NAD(P)H:Quinone acceptor oxidoreductase type 1 , NAD(P)H:menadione oxidoreductase 1 , NAD(P)H:quinone oxireductase , diaphorase (NADH/NADPH) (cytochrome b-5 reductase) , diaphorase-4 , dioxin-inducible 1 , Diaphorase (NADH/NADPH) , NAD(P)H:menadione oxidoreductase , NAD(P)H dehydrogenase (quinone) , NAD(P)H menadione oxidoreductase 1, dioxin inducible , diaphorase 4 (NADH/NADPH) , nicotinamide adenine dinucleotide phosphate diaphorase , diaphorase 4 , NAD(P)H: quinone oxidoreductase 1

GENE ID SPECIES
322506 Danio rerio
468012 Pan troglodytes
549222 Xenopus (Silurana) tropicalis
705635 Macaca mulatta
769737 Gallus gallus
4606922 Azoarcus sp. BH72
5818094 Bordetella petrii DSM 12804
100049751 Xenopus laevis
100172039 Pongo abelii
100528193 Ictalurus punctatus
1728 Homo sapiens
610935 Canis lupus familiaris
24314 Rattus norvegicus
18104 Mus musculus
100286873 Sus scrofa
519632 Bos taurus
100135582 Cavia porcellus
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