Nigericin
Aperçu rapide pour Nigericin (ABIN1027803)
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Fonction
- NALP3 activator
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Attributs du produit
- Induces rapid intracellular acidification.
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Pureté
- >98 %
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Chemical Name
- (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-{(2S,2'R,3'S,5R,5'R)-5'-[(2S,3S,5R,6R)-6-Hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-2,3'-dimethyloctahydro-2,2'-bifuran-5-yl}-9-metho xy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl]methyl}-3-methyltetrahydro-2H-pyran-2-yl]propanoic acid
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Formula
- C40H67NaO11
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Solubility
- Soluble to 50 mM in DMSO and 20 mM in ethanol
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Commentaires
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Source: Synthetic.
Appearance: White to off-white Solid -
Restrictions
- For Research Use only
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Format
- Solid
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Précaution d'utilisation
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
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Conseil sur la manipulation
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
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Stock
- -20 °C
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Sujet
- Nigericin acts as a K and Na ionophore. It stimulates Ca release from mitochondrial stores by disruption of membrane potential.
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Poids moléculaire
- 746.94
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Numéro CAS
- 28643-80-3
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