Epothilone B

N° du produit ABIN1027817

Aperçu rapide pour Epothilone B (ABIN1027817)

Détail du produit

Fonction: Microtubule stabilizer

Attributs du produit: Microtubule stabilizing agent.

Pureté: >98 %

Chemical Name: (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)-1-propen-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione, Patupilone

Formula: C27H41NO6S

Solubility: Soluble to 10 mM in DMSO

Information d'application

Commentaires:

Source: Synthetic.
Appearance: White Solid

Restrictions: For Research Use only

Stockage

Format: Solid

Précaution d'utilisation: Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Conseil sur la manipulation: Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Stock: -20 °C

Détail du antigène

Sujet: Epothilone are a new class of cancer drugs. They prevent cancer cells from dividing by interfering with tubulin. Epithilone B possess the same biological effects as paclitaxel in both invitro and cultured cells, because they share the same binding site. Epothilone has also been shown to induce tubulin polymerization into microtubules without the presence of GTP. And it also causes cell cycle arrest at the G2-M transition phase, leading to eventual cell apoptosis.

Poids moléculaire: 507.68

Numéro CAS: 152044-54-7