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AIRE Produits

(Autoimmune Regulator (AIRE))
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012].

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Catégories AIRE en vedette

AIRE Anticorps

High quality antibodies with extensive validation data.

AIRE Kits ELISA

Reliable ELISA kits for a wide range of species.

AIRE Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

AIRE recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (6)
N° du produit ABIN3022515
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC, FACS
Validations
  • (8)
N° du produit ABIN184780
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
Application WB, IHC
Validations
  • (5)
N° du produit ABIN2779777
Quantité 100 μL
Fiche technique Fiche technique

AIRE recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965095
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954016
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954017
Quantité 96 tests
Fiche technique Fiche technique

AIRE recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3088935
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3137558
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7396196
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits AIRE

Nakasatomi, Maeshima, Mishima, Ikeuchi, Sakairi, Kaneko, Hiromura, Nojima: "Novel approach for the detection of tubular cell migration into the interstitium during renal fibrosis in rats." dans: Fibrogenesis & tissue repair, Vol. 8, pp. 12, (2015) (PubMed).

Suzuki, Suzuki, Nakai, Sembon, Fuchimoto, Onishi: "Transcriptional and histological analyses of the thymic developmental process in the fetal pig." dans: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 63, Issue 2, pp. 215-25, (2014) (PubMed).

Ströbel, Hartmann, Rosenwald, Kalla, Ott, Friedel, Schalke, Kasahara, Tomaru, Marx: "Corticomedullary differentiation and maturational arrest in thymomas." dans: Histopathology, Vol. 64, Issue 4, pp. 557-66, (2014) (PubMed).

Jüngling, Liu, Lesting, Coulon, Sosulina, Reinscheid, Pape: "Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor." dans: The Journal of physiology, Vol. 590, Issue Pt 16, pp. 3701-17, (2012) (PubMed).

Wei, Akerman, Newey, Pan, Clinch, Jacob, Shen, Wilkins, Ellory: "The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism." dans: The Journal of physiology, Vol. 589, Issue Pt 22, pp. 5349-59, (2011) (PubMed).

Yuan, Zhu, Zhou, Chen, Zhu, Ma, He, Tian, Shi: "Role of mast cell activation in inducing microglial cells to release neurotrophin." dans: Journal of neuroscience research, Vol. 88, Issue 6, pp. 1348-54, (2010) (PubMed).

Zelano, Berg, Thams, Hailer, Cullheim: "SynCAM1 expression correlates with restoration of central synapses on spinal motoneurons after two different models of peripheral nerve injury." dans: The Journal of comparative neurology, Vol. 517, Issue 5, pp. 670-82, (2009) (PubMed).

Niki, Oshikawa, Mouri, Hirota, Matsushima, Yano, Han, Bando, Izumi, Matsumoto, Nakayama, Kuroda, Matsumoto: "Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice." dans: The Journal of clinical investigation, Vol. 116, Issue 5, pp. 1292-301, (2006) (PubMed).

Tao, Kupfer, Stewart, Williams-Skipp, Crowell, Patel, Sain, Scheinman: "AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix." dans: Molecular immunology, Vol. 43, Issue 4, pp. 335-45, (2005) (PubMed).

Kumar, Laloraya, Wang, Ruan, Davoodi-Semiromi, Kao, She: "The autoimmune regulator (AIRE) is a DNA-binding protein." dans: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 41357-64, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à AIRE

autoimmune regulator (AaeL_AAEL013794), autoimmune regulator (CpipJ_CPIJ001208), autoimmune regulator (CpipJ_CPIJ001209), autoimmune regulator (AIRE), autoimmune regulator (Aire), autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) (Aire), AIRE1, APECED, APS1, APSI, PGA1

Protein level used designations for AIRE

  • autoimmune regulator
  • autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein
  • autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
  • APECED protein homolog
  • autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog
  • autoimmune regulator AIRE1a
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