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ANGPTL4 Produits

(Angiopoietin-Like 4 (ANGPTL4))

Catégories

This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Jul 2008].

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Catégories ANGPTL4 en vedette

ANGPTL4 Anticorps

High quality antibodies with extensive validation data.

ANGPTL4 Kits ELISA

Reliable ELISA kits for a wide range of species.

ANGPTL4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ANGPTL4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (9)
N° du produit ABIN7433018
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7433021
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
  • (4)
N° du produit ABIN526478
Quantité 50 μg
Fiche technique Fiche technique

ANGPTL4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
N° du produit ABIN6720566
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
N° du produit ABIN6953728
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
N° du produit ABIN6953729
Quantité 96 tests
Fiche technique Fiche technique

ANGPTL4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7273833
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7273832
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
N° du produit ABIN1794453
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits ANGPTL4

Folz, Oh, Blaženović, Richey, Fiehn, Youn: "Interaction of Gut Microbiota and High-Sodium, Low-Potassium Diet in Altering Plasma Triglyceride Profiles Revealed by Lipidomics Analysis." dans: Molecular nutrition & food research, Vol. 63, Issue 24, pp. e1900752, (2020) (PubMed).

Dikker, Çetin Dağ, Şahin, Türkkan, Dağ: "The association of angiopoietin-like peptide 4 levels with obesity and hepatosteatosis in adolescents." dans: Cytokine, Vol. 125, pp. 154802, (2020) (PubMed).

Huang, Xie, Lin, Li, Huang, Wang, Ye: "The downregulation of ANGPTL4 inhibits the migration and proliferation of tongue squamous cell carcinoma." dans: Archives of oral biology, Vol. 71, pp. 144-149, (2017) (PubMed).

Li, Chen, Peng, Wei, Zhao, Diao, He, Liu, Wei, Zhang, Li: "Angiopoietin-Like-4, a Potential Target of Tacrolimus, Predicts Earlier Podocyte Injury in Minimal Change Disease." dans: PLoS ONE, Vol. 10, Issue 9, pp. e0137049, (2015) (PubMed).

Ma, Chen, Li, Peng, Wei, Zhao, Li, Zhu, He, Wei, Li: "Upregulation of podocyte-secreted angiopoietin-like-4 in diabetic nephropathy." dans: Endocrine, Vol. 49, Issue 2, pp. 373-84, (2015) (PubMed).

Wan, Wen, Dong, Tang, Liu, Liu, Tao, Gao, Sun, Cao, Fan, Wu: "Establishment of monoclonal HCC cell lines with organ site-specific tropisms." dans: BMC cancer, Vol. 15, pp. 678, (2015) (PubMed).

Schumacher, Denecke, Braunschweig, Stahlschmidt, Ziegler, Brandenburg, Stope, Martincuks, Vogt, Görtz, Camporeale, Poli, Müller-Newen, Brümmendorf, Ziegler: "Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy." dans: Journal of hematology & oncology, Vol. 8, pp. 64, (2015) (PubMed).

Güneş, Bukan: "Examination of angiopoietin-like protein 4, neuropeptide Y, omentin-1 levels of obese and non-obese patients with polycystic ovary syndrome." dans: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, Vol. 31, Issue 11, pp. 903-6, (2015) (PubMed).

Wang, Zhu, Wang, Yao, Zhao, Liu: "Non-esterified fatty acids promote expression and secretion of angiopoietin-like protein 4 in calf hepatocytes cultured in vitro." dans: Molecular and cellular biochemistry, (2014) (PubMed).

Catoire, Alex, Paraskevopulos, Mattijssen, Evers-van Gogh, Schaart, Jeppesen, Kneppers, Mensink, Voshol, Olivecrona, Tan, Hesselink, Berbée, Rensen, Kalkhoven, Schrauwen, Kersten: "Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 11, pp. E1043-52, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à ANGPTL4

angiopoietin like 4 (ANGPTL4), angiopoietin-like 4 (Angptl4), angiopoietin-like 4 (angptl4), ANGPTL2, ANGPTL4, ARP4, Arp4, Bk89, FIAF, Fiaf, fiaf, HFARP, Hfarp, im:7144703, Ng27, NL2, PGAR, Pgar, Pgarg, pp1158, Pp1158, si:rp71-39b20.7

Protein level used designations for ANGPTL4

  • PPARG angiopoietin related protein
  • angiopoietin-like protein 4
  • angiopoietin-related protein 4
  • fasting-induced adipose factor
  • hepatic angiopoietin-related protein
  • hepatic fibrinogen/angiopoietin-related protein
  • peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein
  • 425O18-1
  • fibrinogen/angiopoietin-related protein
  • major histocompatibility complex region NG27
  • secreted protein Bk89
  • HFARP
  • PPARG angiopoietin-related protein
  • angiopoietin-like 4
  • angiopoietin-like secreted glycoprotein 4
  • angiopoietin-related protein 4-like
  • angiopoietin-like 4 protein
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