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Annexin VII Produits

(Annexin A7 (ANXA7))

Catégories

Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008].

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Catégories Annexin VII en vedette

Annexin VII Anticorps

High quality antibodies with extensive validation data.

Annexin VII Kits ELISA

Reliable ELISA kits for a wide range of species.

Annexin VII Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Annexin VII recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (5)
N° du produit ABIN513369
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (5)
N° du produit ABIN3029978
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7144294
Quantité 100 μL
Fiche technique Fiche technique

Annexin VII recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953788
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN511905
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN509722
Quantité 96 tests
Fiche technique Fiche technique

Annexin VII recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1345200
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121849
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3088982
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Annexin VII

Wang, Gao, Sun, Bai, Ibrahim, Wang, Tang: "In vivo and in vitro effect of hepatocarcinoma lymph node metastasis by upregulation of Annexin A7 and relevant mechanisms." dans: Tumour biology, (2015) (PubMed).

Wang, Yuegao, Bai, Ibrahim, Ma, Zhang, Huang, Wang, Song, Tang: "Evaluation of Annexin A7, Galectin-3 and Gelsolin as possible biomarkers of hepatocarcinoma lymphatic metastasis." dans: Biomedicine & pharmacotherapy, Vol. 68, Issue 3, pp. 259-65, (2014) (PubMed).

Li, Huang, Wang, Zhao, Su, Zhao, Zhang, Zhang, Miao: "Targeting annexin A7 by a small molecule suppressed the activity of phosphatidylcholine-specific phospholipase C in vascular endothelial cells and inhibited atherosclerosis in apolipoprotein E⁻/⁻mice." dans: Cell death & disease, Vol. 4, pp. e806, (2013) (PubMed).

Zhou, Li, Liu, Li, Wang, Shen: "Increased expression of annexin A7 in temporal lobe tissue of patients with refractory epilepsy." dans: Histology and histopathology, Vol. 26, Issue 5, pp. 571-9, (2011) (PubMed).

Satoh, Nakano, Shibata, Maki: "The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner." dans: Biochimica et biophysica acta, Vol. 1600, Issue 1-2, pp. 61-7, (2002) (PubMed).

Salzer, Hinterdorfer, Hunger, Borken, Prohaska: "Ca(++)-dependent vesicle release from erythrocytes involves stomatin-specific lipid rafts, synexin (annexin VII), and sorcin." dans: Blood, Vol. 99, Issue 7, pp. 2569-77, (2002) (PubMed).

Srivastava, Bubendorf, Srikantan, Fossom, Nolan, Glasman, Leighton, Fehrle, Pittaluga, Raffeld, Koivisto, Willi, Gasser, Kononen, Sauter, Kallioniemi, Srivastava, Pollard: "ANX7, a candidate tumor suppressor gene for prostate cancer." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 8, pp. 4575-80, (2001) (PubMed).

Furge, Chen, Cohen: "Annexin VII and annexin XI are tyrosine phosphorylated in peroxovanadate-treated dogs and in platelet-derived growth factor-treated rat vascular smooth muscle cells." dans: The Journal of biological chemistry, Vol. 274, Issue 47, pp. 33504-9, (1999) (PubMed).

Selbert, Fischer, Pongratz, Stewart, Noegel: "Expression and localization of annexin VII (synexin) in muscle cells." dans: Journal of cell science, Vol. 108 ( Pt 1), pp. 85-95, (1995) (PubMed).

Magendzo, Shirvan, Cultraro, Srivastava, Pollard, Burns: "Alternative splicing of human synexin mRNA in brain, cardiac, and skeletal muscle alters the unique N-terminal domain." dans: The Journal of biological chemistry, Vol. 266, Issue 5, pp. 3228-32, (1991) (PubMed).

Synonymes et noms alternatifs relatifs à Annexin VII

annexin A7 (ANXA7), annexin A7 (Anxa7), annexin VII (anxa7), annexin A7 (anxa7), annexin A7 S homeolog (anxa7.S), annexin A7 (PTRG_02166), annexin A7 (BRAFLDRAFT_231082), annexin A7 (PAAG_00136), annexin A7 (MCYG_04180), annexin A7 (VDBG_06328), annexin A7 (MGYG_02426), AI265384, AI316497, ANX7, Anx7, anxa7, ANXA7, MGC76267, MGC82023, MGC83033, SNX, SYNEXIN, synexin

Protein level used designations for Annexin VII

  • annexin VII
  • annexin-7
  • annexin A7
  • synexin
  • annexin A7-like
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