ANTXR1 Produits
(anthrax Toxin Receptor 1 (ANTXR1))
Catégories
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008].
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Catégories ANTXR1 en vedette
ANTXR1 Anticorps
High quality antibodies with extensive validation data.
ANTXR1 Kits ELISA
Reliable ELISA kits for a wide range of species.
ANTXR1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ANTXR1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (2)
N° du produit
ABIN544900
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ICC
Validations
- (2)
- (2)
N° du produit
ABIN541433
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
N° du produit
ABIN392154
Quantité
400 μL
Fiche technique
Fiche technique
ANTXR1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964899
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1122056
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1122057
Quantité
96 tests
Fiche technique
Fiche technique
ANTXR1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121857
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345159
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345161
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ANTXR1
: "Structural basis for anthrax toxin receptor 1 recognition by Seneca Valley Virus." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 46, pp. E10934-E10940, (2019) (PubMed).: "Isolated tumor endothelial cells maintain specific character during long-term culture." dans: Biochemical and biophysical research communications, Vol. 394, Issue 4, pp. 947-54, (2010) (PubMed).
: "The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin." dans: Cell, Vol. 124, Issue 6, pp. 1141-54, (2006) (PubMed).
: "Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton." dans: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23227-36, (2006) (PubMed).
: "Receptor-specific requirements for anthrax toxin delivery into cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13278-83, (2005) (PubMed).
: "TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen." dans: Experimental cell research, Vol. 305, Issue 1, pp. 133-44, (2005) (PubMed).
: "NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells." dans: The Biochemical journal, Vol. 384, Issue Pt 2, pp. 281-6, (2004) (PubMed).
: "TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI)." dans: Cancer research, Vol. 64, Issue 3, pp. 817-20, (2004) (PubMed).
: "Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I." dans: The Journal of biological chemistry, Vol. 276, Issue 51, pp. 48404-9, (2001) (PubMed).
: "Mitochondrial endonuclease G is important for apoptosis in C. elegans." dans: Nature, Vol. 412, Issue 6842, pp. 90-4, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à ANTXR1
anthrax toxin receptor 1 (ANTXR1), anthrax toxin receptor 1 (Antxr1), 2310008J16Rik, 2810405N18Rik, Antrx1, ANTXR1, ATR, TEM8, Tem8Protein level used designations for ANTXR1
- anthrax toxin receptor 1
- tumor endothelial marker 8
- anthrax toxin receptor 1-like
- 2310008J16Rik
- 2810405N18Rik
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