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CD13 anticorps (Biotin)

ANPEP Reactivité: Humain, Non-Human Primate FACS, IHC (fro), IP Hôte: Souris Monoclonal WM15 Biotin
N° du produit ABIN1027683
  • Antigène Voir toutes CD13 (ANPEP) Anticorps
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    Reactivité
    • 155
    • 51
    • 22
    • 10
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Non-Human Primate
    Hôte
    • 98
    • 63
    • 12
    • 1
    • 1
    Souris
    Clonalité
    • 118
    • 54
    Monoclonal
    Conjugué
    • 68
    • 21
    • 16
    • 12
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD13 est conjugé à/à la Biotin
    Application
    • 105
    • 66
    • 36
    • 35
    • 35
    • 33
    • 21
    • 17
    • 14
    • 14
    • 13
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
    Specificité
    The antibody WM15 recognises an extracellular epitope of human CD13 cell surface glycoprotein, a 150 kDa molecule expressed on granulocytes, endothelial cells, epithelial cells and myeloid progenitors.
    Réactivité croisée (Details)
    Human, Non-Human Primates
    Purification
    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
    Immunogène
    Human AML cells
    Clone
    WM15
    Isotype
    IgG1
    Top Product
    Discover our top product ANPEP Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 3-5 μg/mL.
    Commentaires

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Avoid prolonged exposure to light.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • McCormack, Muji?, Osdal, Bruserud, Gjertsen: "Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia." dans: Blood, Vol. 121, Issue 7, pp. e34-42, (2013) (PubMed).

    Favaloro, Browning, Facey: "CD13 (GP150; aminopeptidase-N): predominant functional activity in blood is localized to plasma and is not cell-surface associated." dans: Experimental hematology, Vol. 21, Issue 13, pp. 1695-701, (1993) (PubMed).

    Bradstock, Favaloro, Kabral, Kerr, Hughes, Berndt, Musgrove: "Human myeloid differentiation antigens identified by monoclonal antibodies: expression on leukemic cells." dans: Pathology, Vol. 17, Issue 3, pp. 392-9, (1986) (PubMed).

    Bradstock, Favaloro, Kabral, Kerr, Hughes, Musgrove: "Myeloid progenitor surface antigen identified by monoclonal antibody." dans: British journal of haematology, Vol. 61, Issue 1, pp. 11-20, (1985) (PubMed).

  • Antigène
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    Autre désignation
    CD13 (ANPEP Produits)
    Synonymes
    anticorps APN, anticorps CD13, anticorps GP150, anticorps LAP1, anticorps P150, anticorps PEPN, anticorps A2AP, anticorps AAP, anticorps ALPHA-2-PI, anticorps API, anticorps PLI, anticorps AAT1, anticorps ALT1, anticorps GPT1, anticorps Gpt1, anticorps Apn, anticorps pepN, anticorps SC8E4A.13, anticorps 1300007J06Rik, anticorps 2310022B03Rik, anticorps ALT, anticorps Gpt-1, anticorps AP-M, anticorps AP-N, anticorps Cd13, anticorps Apm, anticorps KZP, anticorps Lap1, anticorps rAPN, anticorps APDE, anticorps p150, anticorps anpep, anticorps fb64c05, anticorps wu:fb64c05, anticorps zgc:136771, anticorps alanyl aminopeptidase, membrane, anticorps serpin family F member 2, anticorps glutamic--pyruvic transaminase, anticorps aminopeptidase N, anticorps aminopeptidase, anticorps aminopeptidase n, anticorps glutamic pyruvic transaminase, soluble, anticorps alanyl (membrane) aminopeptidase, anticorps membrane alanyl aminopeptidase, anticorps alanyl (membrane) aminopeptidase b, anticorps alanyl aminopeptidase, membrane L homeolog, anticorps ANPEP, anticorps SERPINF2, anticorps GPT, anticorps Gpt, anticorps Apn2, anticorps Apn1, anticorps SCO2643, anticorps pepN, anticorps Shewana3_0897, anticorps Alvin_1024, anticorps Ndas_3413, anticorps Saut_1544, anticorps Fbal_1877, anticorps ML5_3424, anticorps Despr_1988, anticorps Mesop_5365, anticorps Anpep, anticorps LOC101744250, anticorps anpepb, anticorps anpep.L
    Sujet
    Alanyl aminopeptidase, membrane,CD13 (aminopeptidase N, APN) is a 150 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. This metalloprotease preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 has also role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas.,Aminopeptidase N, APN, PEPN, ANPEP, gp150, LAP1
    ID gène
    290
    UniProt
    P15144
    Pathways
    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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