CLCN3 anticorps (AA 98-115)

N° du produit ABIN1027722

Cet anticorps anti-CLCN3 est un anticorps Souris Monoclonal détectant CLCN3 dans WB, IHC, ICC et IF. Adapté pour Rat.

Aperçu rapide pour CLCN3 anticorps (AA 98-115) (ABIN1027722)

Antigène: CLCN3 (Chloride Channel 3 (CLCN3))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CLCN3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: S258-5

Détail du produit anti-CLCN3 anticorps

Épitope: AA 98-115

Specificité: Detects ~90 kDa. Does not cross-react with Clcn4 or Clcn5 (based on KO validation results).

Réactivité croisée: Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Synthetic peptide amino acids 98-115 (cytoplasmic N-terminus) of rat Clcn3

Isotype: IgG1

Information d'application

Indications d'application:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN1027722 was sufficient for detection of Clcn3 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur CLCN3

Antigène: CLCN3 (Chloride Channel 3 (CLCN3))

Autre désignation: ClCN3

Sujet: Clcn3 mediates the exchange of chloride ions against protons, and functions as an antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. It may play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could also help neuronal cells to establish short-term memory.

ID gène: 84360

NCBI Accession: NP_445815

UniProt: P51792