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SARS-CoV Spike anticorps (Intermediate Domain 1)

SARS-CoV S Reactivité: SARS Coronavirus (SARS-CoV) ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1031189
  • Antigène Voir toutes SARS-CoV Spike (SARS-CoV S) Anticorps
    SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))
    Épitope
    • 15
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Intermediate Domain 1
    Reactivité
    • 43
    • 16
    SARS Coronavirus (SARS-CoV)
    Hôte
    • 40
    • 3
    Lapin
    Clonalité
    • 40
    • 3
    Polyclonal
    Conjugué
    • 27
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SARS-CoV Spike est non-conjugé
    Application
    • 35
    • 25
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    Homologie
    Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (identity 56%, homology 69%)
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    Anti-SARS-CoV Spike antibody was raised against a peptide corresponding to 16 amino acids near the center of SARS-CoV Spike glycoprotein.
    The immunogen is located within amino acids 410-460 of SARS-CoV Spike.
    Isotype
    IgG
    Top Product
    Discover our top product SARS-CoV S Anticorps primaire
  • Indications d'application
    SARS-CoV Spike antibody can be used for the detection of SARS-CoV Spike protein in ELISA. It will detect 2 ng of free peptide at 1 μg/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    The antibody is supplied in PBS containing 0.02% sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    The antibody can be stored at 4 ˚ C for three months and -20 ˚ C, stable for up to one year.
    Date de péremption
    12 months
  • Antigène
    SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))
    Autre désignation
    SARS-CoV Spike (SARS-CoV S Produits)
    Classe de substances
    Viral Protein
    Sujet
    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection. The spike protein is the major target for neutralizing antibodies and vaccine development. The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19. The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein .
    ID gène
    1489668
    NCBI Accession
    P59594
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