DGKA anticorps

N° du produit ABIN1042452

Cet anticorps anti-DGKA est un anticorps Souris Monoclonal détectant DGKA dans WB et IP. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour DGKA anticorps (ABIN1042452)

Antigène: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DGKA est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: M6

Détail du produit anti-DGKA anticorps

Specificité: M6 is directed against the C-terminal portion (part of the catalytic domain) of rat DGKa.

Attributs du produit: Other

Purification: Purified

Information d'application

Indications d'application: M6 is useful for immunoprecipitation and western blot. Optimal antibody dilution should be determined by titration.

Commentaires:

M6 is a mouse monoclonal IgG1 antibody derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with an Escherichia coli cell-expressed, affinity-purified glutathione S-transferase fusion protein of a C-terminal portion (part of the catalytic domain) of rat DGKu.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.09% sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-DGKA (ABIN1042452)

Guckes, McCarthy, Brahim: "Use of endosseous implants in a 3-year-old child with ectodermal dysplasia: case report and 5-year follow-up." dans: Pediatric dentistry, Vol. 19, Issue 4, pp. 282-5, (1997) (PubMed).

Détails sur DGKA

Antigène: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Autre désignation: DGKa

Sujet: Diacylglycerol kinase alpha is an enzyme that in humans is encoded by the DGKA gene. The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Tissue specificity: lymphocytes and oligodendroglial cells. Diacylglycerol kinases are involved in cell signaling, either as regulators of diacylglycerol levels or as intracellular signal-generating enzymes.