Progerin (AA 604-611) anticorps

N° du produit ABIN1042661

Détail du produit

Antigène: Progerin

Épitope: AA 604-611

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA

Séquence: GAQSPQNC

Specificité: Specifically recognizes Progerin (LaminAdelta50) and does not cross-react with endogenous prelamin A

Purification: Protein G

Immunogène: Synthetic peptide conjugated to KLH derived from within residues 604 - 611 (GAQSPQNC) at the C terminus of Human Progerin

Clone: 13A4D4

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal antibody dilution should be determined by titration, however as a guideline try,WB: 1/500. Detects a band of approximately 70 kDa

Commentaires:

Myeloma, fusion partners: X63-Ag8.653

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Référence

Liu, Barkho, Ruiz, Diep, Qu, Yang, Panopoulos, Suzuki, Kurian, Walsh, Thompson, Boue, Fung, Sancho-Martinez, Zhang, Yates, Izpisua Belmonte: "Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome." dans: Nature, Vol. 472, Issue 7342, pp. 221-5, (2011) (PubMed).

Détail du antigène

Antigène: Progerin

Autre désignation: Progerin 

ID gène: 24380

OMIM: 150330