Interleukin 17a anticorps (Biotin)

N° du produit ABIN1043792

N° du produit (Fournisseur): 209-306-b32

L’anticorps Souris Monoclonal anti-Interleukin 17a a été validé pour ELISA, WB et FACS. Il convient pour détecter Interleukin 17a dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour Interleukin 17a anticorps (Biotin) (ABIN1043792)

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Interleukin 17a est conjugé à/à la Biotin

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Clone: 4H1524-1

Détail du produit anti-Interleukin 17a anticorps (Biotin)

N° du produit (Fournisseur): 209-306-b32

Fournisseur: Rockland

Fonction: IL-17A Biotin Conjugated Antibody

Réactivité croisée (Details): This antibody is specific for human IL-17A protein.

Attributs du produit: Synonyms: mouse anti-Interleukin-17A biotin conjugated antibody, mouse anti-IL-17A biotin conjugated antibody, IL-17A, Interleukin-17A, Cytotoxic T-Lymphocyte-associated Antigen 8, CTLA8, Interleukin-17, IL17, IL-17, Interleukin17

Purification: This product was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above.

Immunogène:

Immunogen: Anti-IL-17A (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17A produced in E.coli followed by hybridoma development.

Immunogen Type: Recombinant Protein

Isotype: IgG2b

Labeling Ratio: 10-20

Information d'application

Indications d'application:

Flow Cytometry Dilution: User Optimized

Application Note: This purified antibody has been tested by Western Blot and suitable for use in FLOW. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: User Optimized

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution Volume: 100 μL

Reconstitution Buffer: Restore with deionized water (or equivalent)

Concentration: 1.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to restoration.   Restore with 0.1 mL of deionized water (or equivalent). For extended storage aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.

Date de péremption: 12 months

Références pour anticorps anti-Interleukin 17a (Biotin) (ABIN1043792)

Paust, Turner, Steinmetz, Peters, Heymann, Hölscher, Wolf, Kurts, Mittrücker, Stahl, Panzer: "The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis." dans: Journal of the American Society of Nephrology : JASN, Vol. 20, Issue 5, pp. 969-79, (2009) (PubMed).

Détails sur Interleukin 17a

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Autre désignation: IL17A

Sujet: Background: IL17-A (also known as Interleukin-17) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC. Anti-IL-17A antibody is ideal for investigators involved in Immunology research.

ID gène: 3605

NCBI Accession: NP_002181

UniProt: Q16552