RRAGA anticorps (AA 1-247) (FITC)

N° du produit ABIN1046029

Cet anticorps Lapin Polyclonal détecte spécifiquement RRAGA dans ELISA et WB. Il présente une réactivité envers Humain.

Aperçu rapide pour RRAGA anticorps (AA 1-247) (FITC) (ABIN1046029)

Antigène: RRAGA (Ras-Related GTP Binding A (RRAGA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRAGA est conjugé à/à la FITC

Application: ELISA, Western Blotting (WB)

Détail du produit anti-RRAGA anticorps (FITC)

Épitope: AA 1-247

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ras-related GTP-binding protein A protein (1-247AA)

Isotype: IgG

Information d'application

Indications d'application: Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze and thaw cycles. Product is photosensitive and should be protected from light.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RRAGA

Antigène: RRAGA (Ras-Related GTP Binding A (RRAGA))

Autre désignation: RRAGA

Sujet:

Background: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

Aliases: Adenovirus E3 14.7 kDa-interacting protein 1 antibody, FIP-1 antibody, Rag A antibody, RagA antibody, Ras-related GTP-binding protein A antibody, RRAGA antibody, RRAGA_HUMAN antibody

UniProt: Q7L523