Myc Target 1 anticorps (C-Term)

N° du produit ABIN1077374

L’anticorps Lapin Polyclonal anti-Myc Target 1 a été validé pour WB, ELISA et IF. Il convient pour détecter Myc Target 1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Myc Target 1 anticorps (C-Term) (ABIN1077374)

Antigène: Myc Target 1 (MYCT1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myc Target 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-Myc Target 1 anticorps

Épitope: C-Term

Specificité: At least two isoforms of MYCT1 are known to exist, this antibody will detect both isoforms.

Purification: Affinity chromatography purified via peptide column

Immunogène: MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1.

Isotype: IgG

Information d'application

Indications d'application: MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Commentaires:

(CT) Myc target protein 1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: MYCT1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur Myc Target 1

Antigène: Myc Target 1 (MYCT1)

Autre désignation: MYCT1

Sujet: MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
Synonyms: Myc target protein 1, myc target in myeloid cells 1, MTLC, MT-MC1

Poids moléculaire: 26 kDa

ID gène: 80177

NCBI Accession: NP_079383