Myc Target 1 anticorps (C-Term)

N° du produit ABIN1077374

Détail du produit anti-Myc Target 1 anticorps

Antigène: Myc Target 1 (MYCT1)

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myc Target 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: At least two isoforms of MYCT1 are known to exist, this antibody will detect both isoforms.

Purification: Affinity chromatography purified via peptide column

Immunogène: MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1.

Isotype: IgG

Information d'application

Indications d'application: MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Commentaires:

(CT) Myc target protein 1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: MYCT1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur Myc Target 1

Antigène: Myc Target 1 (MYCT1)

Autre désignation: MYCT1 (MYCT1 Produits)

Synonymes: anticorps MYCT1, anticorps MGC147166, anticorps si:dkey-12h9.2, anticorps MTLC, anticorps 1110020B04Rik, anticorps AI225941, anticorps AI642973, anticorps Mtmc1, anticorps myc target 1, anticorps MYC target 1, anticorps myc target 1a, anticorps MYCT1, anticorps myct1, anticorps myct1a, anticorps Myct1

Sujet: MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
Synonyms: Myc target protein 1, myc target in myeloid cells 1, MTLC, MT-MC1

Poids moléculaire: 26 kDa

ID gène: 80177

NCBI Accession: NP_079383