SHROOM1 anticorps (C-Term)
Aperçu rapide pour SHROOM1 anticorps (C-Term) (ABIN1077406)
Antigène
Voir toutes SHROOM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- SHROOM1 antibody is human, mouse and rat reactive. At least three isoforms of SHROOM1 are known to exist, this antibody will detect only the two largest isoforms. SHROOM1 antibody is predicted to not cross-react with other SHROOM family members.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- Rabbit polyclonal SHROOM1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SHROOM1.
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Isotype
- IgG
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Indications d'application
- SHROOM1 antibody can be used for detection of SHROOM1 by Western blot at 1 - 2 μg/mL.
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Commentaires
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(CT) SHROOM family member 1
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 0.02 % Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Stock
- 4 °C
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Stockage commentaire
- SHROOM1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
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Date de péremption
- 12 months
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- SHROOM1 (Shroom Family Member 1 (SHROOM1))
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Autre désignation
- SHROOM1
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Sujet
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SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.
Synonyms: SHROOM family member 1, Shroom, apical protein 2, APXL2 -
Poids moléculaire
- 94 kDa
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ID gène
- 134549
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NCBI Accession
- NP_001166171
Antigène
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