VTCN1 anticorps

N° du produit ABIN1077428

L’anticorps Lapin Monoclonal anti-VTCN1 a été validé pour WB et ELISA. Il convient pour détecter VTCN1 dans des échantillons de Humain et Souris.

Aperçu rapide pour VTCN1 anticorps (ABIN1077428)

Antigène: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp VTCN1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-VTCN1 anticorps

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal VTCN1 antibody was raised against an 18 amino acid peptide near the center of human VTCN1.

Isotype: IgG

Information d'application

Indications d'application: VTCN1 antibody can be used for detection of VTCN1 by Western blot at 1 - 2 μg/mL.

Commentaires:

(IN) V-set domain containing T cell activation inhibitor 1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: VTCN1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur VTCN1

Antigène: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Autre désignation: VTCN1

Sujet: T cell immunity plays a critical role in host immune surveillance of tumour cell growth and metastatic spread. VTCN1, also known as B7-H4, is a member of the B7 family of immune regulatory molecules. Expressed primarily on the membrane of lymphoid cells, VTCN1 is an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of VTCN1 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumour cells suppress T cell immunity and facilitate tumour progression. VTCN1 may thus be a useful biomarker for the early detection of ovarian cancer.
Synonyms: V-set domain containing T cell activation inhibitor 1, T cell costimulatory molecule B7x, B7-H4, B7H4, B7S1, B7X

Poids moléculaire: 31 kDa (calculated)

ID gène: 79679

NCBI Accession: NP_078902