VTCN1 anticorps
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- Antigène Voir toutes VTCN1 Anticorps
- VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp VTCN1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Rabbit polyclonal VTCN1 antibody was raised against an 18 amino acid peptide near the center of human VTCN1.
- Isotype
- IgG
- Top Product
- Discover our top product VTCN1 Anticorps primaire
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- Indications d'application
- VTCN1 antibody can be used for detection of VTCN1 by Western blot at 1 - 2 μg/mL.
- Commentaires
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(IN) V-set domain containing T cell activation inhibitor 1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- VTCN1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Date de péremption
- 12 months
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- Antigène
- VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
- Autre désignation
- VTCN1 (VTCN1 Produits)
- Synonymes
- anticorps B7h4, anticorps B7s1, anticorps B7x, anticorps BC032925, anticorps B7-H4, anticorps B7H4, anticorps B7S1, anticorps B7X, anticorps B7h.5, anticorps PRO1291, anticorps VCTN1, anticorps RGD1311204, anticorps V set domain containing T cell activation inhibitor 1 L homeolog, anticorps V-set domain containing T cell activation inhibitor 1, anticorps V-set domain containing T-cell activation inhibitor 1, anticorps V set domain containing T cell activation inhibitor 1, anticorps vtcn1.L, anticorps VTCN1, anticorps vtcn1, anticorps Vtcn1
- Sujet
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T cell immunity plays a critical role in host immune surveillance of tumour cell growth and metastatic spread. VTCN1, also known as B7-H4, is a member of the B7 family of immune regulatory molecules. Expressed primarily on the membrane of lymphoid cells, VTCN1 is an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of VTCN1 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumour cells suppress T cell immunity and facilitate tumour progression. VTCN1 may thus be a useful biomarker for the early detection of ovarian cancer.
Synonyms: V-set domain containing T cell activation inhibitor 1, T cell costimulatory molecule B7x, B7-H4, B7H4, B7S1, B7X - Poids moléculaire
- 31 kDa (calculated)
- ID gène
- 79679
- NCBI Accession
- NP_078902
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