CCL4 anticorps

N° du produit ABIN1077439

Détail du produit anti-CCL4 anticorps

Antigène: CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CCL4 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal CCL4 antibody was raised against a 15 amino acid peptide near the center of human CCL4.

Isotype: IgG

Information d'application

Indications d'application: CCL4 antibody can be used for detection of CCL4 by Western blot at 1 - 2 μg/mL.

Commentaires:

(IN) Chemokine (C-C motif) ligand 4

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: CCL4 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur CCL4

Antigène: CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

Autre désignation: CCL4 (CCL4 Produits)

Synonymes: anticorps ACT2, anticorps AT744.1, anticorps G-26, anticorps HC21, anticorps LAG-1, anticorps LAG1, anticorps MIP-1-beta, anticorps MIP1B, anticorps MIP1B1, anticorps SCYA2, anticorps SCYA4, anticorps CCL4, anticorps K203, anticorps Mip1-b, anticorps Scya4, anticorps MIP-1beta, anticorps MIP-1BETA, anticorps MIP1b, anticorps SCY4A, anticorps Act-2, anticorps MIP-1B, anticorps Mip1b, anticorps ACT-2, anticorps AT744.2, anticorps CCL4L, anticorps SCYA4L, anticorps SCYA4L1, anticorps SCYA4L2, anticorps C-C motif chemokine ligand 4, anticorps chemokine (C-C motif) ligand 4, anticorps chemokine (C-C motif) ligand 4-like 1, anticorps C-C motif chemokine ligand 4 like 1, anticorps CCL4, anticorps Ccl4, anticorps CCL4L1

Sujet: CCL4, also known as macrophage inflammatory protein 1-beta (MIP1B), belongs to the intercrine beta (chemokine CC) family. Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells. While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ, with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes. Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells.
Synonyms: C-C motif ligand 4, macrophage inflammatory protein 1-beta, MIP1-beta, MIP1B, MIP1B1, ACT2, AT744.1, G-26, HC21, lymphocyte-activation gene 1, LAG-1, LAG1, SCYA2, SCYA4

Poids moléculaire: 10 kDa (calculated)

ID gène: 6351

NCBI Accession: NP_002975