Annexin a1 anticorps (AA 144-248)

N° du produit ABIN1098115

Cet anticorps Souris Monoclonal détecte spécifiquement Annexin a1 dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Singe. Il a été cité dans 2+ publications.

Aperçu rapide pour Annexin a1 anticorps (AA 144-248) (ABIN1098115)

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivité: Humain, Souris, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Annexin a1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 2F1

Détail du produit anti-Annexin a1 anticorps

Épitope: AA 144-248

Fonction: ANXA1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human ANXA1 (AA: 144-248 ) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Annexin a1 (ABIN1098115)

Nair, Hande, Lim: "Annexin-1 protects MCF7 breast cancer cells against heat-induced growth arrest and DNA damage." dans: Cancer letters, Vol. 294, Issue 1, pp. 111-7, (2010) (PubMed).

Li, Shen, Huang, Huang, Wang, Wu: "Annexin-I overexpression is associated with tumour progression and independently predicts inferior disease-specific and metastasis-free survival in urinary bladder urothelial carcinoma." dans: Pathology, Vol. 42, Issue 1, pp. 43-9, (2009) (PubMed).

Détails sur Annexin a1

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Autre désignation: ANXA1

Sujet: Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

Poids moléculaire: 38.7 kDa

UniProt: P04083

Pathways: Hormone Transport