CD6 anticorps (AA 472-668)

N° du produit ABIN1098118

Cet anticorps Souris Monoclonal détecte spécifiquement CD6 dans IHC et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour CD6 anticorps (AA 472-668) (ABIN1098118)

Antigène: CD6

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD6 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: 6B9

Détail du produit anti-CD6 anticorps

Épitope: AA 472-668

Fonction: CD6 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD6 (AA: 472-668) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CD6 (ABIN1098118)

Alonso, Buors, Le Dantec, Hillion, Pers, Saraux, Montero, Marianowski, Loisel, Devauchelle, Youinou, Renaudineau: "Aberrant expression of CD6 on B-cell subsets from patients with Sjögren's syndrome." dans: Journal of autoimmunity, Vol. 35, Issue 4, pp. 336-41, (2010) (PubMed).

Sarrias, Farnós, Mota, Sánchez-Barbero, Ibáñez, Gimferrer, Vera, Fenutría, Casals, Yélamos, Lozano: "CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 28, pp. 11724-9, (2007) (PubMed).

Détails sur CD6

Antigène: CD6

Autre désignation: CD6

Sujet: This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 71.8 kDa

ID gène: 923

UniProt: P30203