RAG1 anticorps (AA 818-868)
Aperçu rapide pour RAG1 anticorps (AA 818-868) (ABIN1098121)
Antigène
Voir toutes RAG1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 818-868
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Fonction
- RAG1 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human RAG1 (AA: 818-868) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
- ELISA: 1/10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." dans: PLoS ONE, Vol. 6, Issue 5, pp. e20475, (2011) (PubMed).
: "The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3." dans: Immunology letters, Vol. 136, Issue 2, pp. 156-62, (2011) (PubMed).
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: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." dans: PLoS ONE, Vol. 6, Issue 5, pp. e20475, (2011) (PubMed).
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- RAG1 (Recombination Activating Gene 1 (RAG1))
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Autre désignation
- RAG1
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Sujet
- The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.
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Poids moléculaire
- 119 kDa
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ID gène
- 5896
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UniProt
- P15918
Antigène
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