PPY anticorps (AA 1-95)

N° du produit ABIN1098139

Cet anticorps Souris Monoclonal détecte spécifiquement PPY dans ELISA et FACS. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour PPY anticorps (AA 1-95) (ABIN1098139)

Antigène: PPY (Pancreatic Polypeptide (PPY))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PPY est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 2G5D12

Détail du produit anti-PPY anticorps

Épitope: AA 1-95

Fonction: PPY Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PPY (AA: 1-95) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-PPY (ABIN1098139)

Banerjee, Onyuksel: "Human pancreatic polypeptide in a phospholipid-based micellar formulation." dans: Pharmaceutical research, Vol. 29, Issue 6, pp. 1698-711, (2012) (PubMed).

Naessén, Carlström, Holst, Hellström, Hirschberg: "Women with bulimia nervosa exhibit attenuated secretion of glucagon-like peptide 1, pancreatic polypeptide, and insulin in response to a meal." dans: The American journal of clinical nutrition, Vol. 94, Issue 4, pp. 967-72, (2011) (PubMed).

Détails sur PPY

Antigène: PPY (Pancreatic Polypeptide (PPY))

Autre désignation: PPY

Sujet: This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products, the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.

Poids moléculaire: 10.4 kDa

ID gène: 5539

UniProt: P01298

Pathways: Feeding Behaviour