MMP2 anticorps (AA 242-396)

N° du produit ABIN1098146

2+ publications sont disponibles pour ce produit. L’anticorps anti-MMP2 Monoclonal produit chez le Souris a été validé pour WB et ELISA. Il convient pour la détection de MMP2 dans des échantillons provenant de Humain. }

Aperçu rapide pour MMP2 anticorps (AA 242-396) (ABIN1098146)

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 4D1E2

Détail du produit anti-MMP2 anticorps

Épitope: AA 242-396

Fonction: MMP2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human MMP2 (AA: 242-396) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MMP2 (ABIN1098146)

Langers, Verspaget, Hawinkels, Kubben, van Duijn, van der Reijden, Hardwick, Hommes, Sier: "MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients." dans: British journal of cancer, Vol. 106, Issue 9, pp. 1495-8, (2012) (PubMed).

Hajighasemi: "Profiles of MMP-2 expression in Jurkat, Molt-4 and U937 cells." dans: Iranian journal of immunology : IJI, Vol. 8, Issue 2, pp. 120-6, (2011) (PubMed).

Détails sur MMP2

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Autre désignation: MMP2

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 73.8 kDa

ID gène: 4313

UniProt: P08253

Pathways: Activation of Innate immune Response