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ACIN1 anticorps (N-Term)

ACIN1 Reactivité: Humain WB, IP Hôte: Souris Monoclonal 3H8 unconjugated
N° du produit ABIN1105223
  • Antigène Voir toutes ACIN1 Anticorps
    ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))
    Épitope
    • 9
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-523, N-Term
    Reactivité
    • 39
    • 22
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 36
    • 3
    Souris
    Clonalité
    • 36
    • 3
    Monoclonal
    Conjugué
    • 32
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ACIN1 est non-conjugé
    Application
    • 30
    • 19
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Specificité
    This antibody reacts withAcinusL.
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Does not react with mouse (WR19L, NIH3T3) or hamster (CHO).
    Purification
    Protein A agarose beads
    Immunogène
    GST-human AcinusL fusion protein corresponding to N-terminal amino acids (1~523 a.a.)
    Clone
    3H8
    Isotype
    IgG1
    Top Product
    Discover our top product ACIN1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    Agent conservateur
    Without preservative
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store (in aliquots) at -20 °C.
  • Antigène
    ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))
    Autre désignation
    Acinus / ACIN1 (ACIN1 Produits)
    Synonymes
    anticorps acinus, anticorps acinusb, anticorps fi14c05, anticorps wu:fe06a10, anticorps wu:fi14c05, anticorps acinusa, anticorps acinusl, anticorps ik:tdsubc_2g5, anticorps si:zc14a17.12, anticorps wu:fb04g06, anticorps wu:fb40f03, anticorps wu:fb68h03, anticorps wu:fb80f07, anticorps wu:fc12e10, anticorps xx:tdsubc_2g5, anticorps acn, anticorps ACINUS, anticorps ACN, anticorps fSAP152, anticorps 2610036I19Rik, anticorps 2610510L13Rik, anticorps Acinus, anticorps Acn, anticorps C79325, anticorps acinusL, anticorps acinusS, anticorps mKIAA0670, anticorps apoptotic chromatin condensation inducer 1b, anticorps apoptotic chromatin condensation inducer 1a, anticorps apoptotic chromatin condensation inducer 1, anticorps apoptotic chromatin condensation inducer 1 S homeolog, anticorps acin1b, anticorps acin1a, anticorps acin1, anticorps ACIN1, anticorps acin1.S, anticorps Acin1
    Sujet
    Chromatin condensation and nuclear fragmentation (CCNF) are hallmarks of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase-activated DNase (CAD/DFF40) and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (Apoptotic Chromatin Condensation Inducer in the Nucleus). The 220 kDa Acinus protein is cleaved by caspase-3 and an additional unknown protease to generate a 17 kDa peptide that which causes chromatin condensation in vitro when added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS, and AcinusS'. Acinus is ubiquitously expressed.Synonyms: Apoptotic chromatin condensation inducer in the nucleus, KIAA0670
    Poids moléculaire
    220 kDa
    ID gène
    22985
    NCBI Accession
    NP_001158286
    UniProt
    Q9UKV3
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