ADAMTSL1 anticorps (N-Term)

N° du produit ABIN1105253

L’anticorps anti-ADAMTSL1 Monoclonal Souris est utilisé pour la détection de ADAMTSL1 dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour ADAMTSL1 anticorps (N-Term) (ABIN1105253)

Antigène: ADAMTSL1 (ADAMTS-Like 1 (ADAMTSL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ADAMTSL1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: IBL-5-25

Détail du produit anti-ADAMTSL1 anticorps

Épitope: N-Term

Specificité: Monoclonal antibody 1B2-8-2 reacts with Punctin-1 (ADAMTSL-1). It recognizes the first thrombospondin repeat near the N-terminal and reacts with molecular species of 55 kDa or a doublet of 55 k Da and 60 kDa (glycosylated form). Note that proteolysis of Punctin-1 has been described and additional smaller bands may also be obtained.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Protein G, 0.02 % sodium azide, 0.1 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Détails sur ADAMTSL1

Antigène: ADAMTSL1 (ADAMTS-Like 1 (ADAMTSL1))

Autre désignation: ADAMTSL1

Sujet: Punctin-1 is a secreted molecule resembling members of the family of proteases designated ADAMTS (a disintegrin-like and metalloprotease domain with thrombospondin type I motif). ADAMTS proteases are secreted enzymes that consist of a metalloprotease domain (which provides the catalytic activity) and ancillary domains (which provide substrate, cell or extracellular matrix activity). Punctin-1 lacks the pro-metalloprotease and the disintegrin-like domain typical of this family but contains other ADAMTS domains in precise order including 4 thrombospondin-I repeats. Punctin-1 is an extracellular matrix protein in tissues and deposited into the cell substratum and localized towards the periphery of transfected cells. Punctin-1 and Punctin-2 (ADAMTSL-3) are the first members of a novel family of ADAMTS-like proteins that appear to have important functions in the extracellular matrix.Synonyms: ADAMTS-like protein 1, ADAMTSL-1, ADAMTSR1

ID gène: 92949

NCBI Accession: NP_001035362

UniProt: Q8N6G6